DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6712 and rpf1

DIOPT Version :9

Sequence 1:	NP_477479.1	Gene:	CG6712 / 34631	FlyBaseID:	FBgn0032408	Length:	394	Species:	Drosophila melanogaster
Sequence 2:	NP_001002160.2	Gene:	rpf1 / 415250	ZFINID:	ZDB-GENE-040625-177	Length:	355	Species:	Danio rerio

Alignment Length:	366	Identity:	162/366 - (44%)
Similarity:	230/366 - (62%)	Gaps:	27/366 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 TDSSDEEAASSSK-KTAKQGEASEDLKEEDDDDDEEENDDDDEEEDDDDDDDKKTRIPVLNP--- 99
            |||:.....|..| ||.|.....:.:|...::.|:.|.:..:|         |....|...|
Zfish     4 TDSTSSGHVSKKKSKTKKLKRTMKAVKAPVEEMDQAECEVKEE---------KSASGPCFPPTFS 59

  Fly   100 LSWMRNKEQRLALYKKMKKEKHKKKMQ-------ERRARRKAGVPANPGHTIESLREKDQTEVAN 157
            :|.::||::|..::.|:|:||.||:|:       ||:|......|.....|||:.|..|:|.|
Zfish    60 VSEIKNKQRRHTMFLKLKEEKRKKRMELKKKKKKERKALGDKAPPKEVPKTIENQRIYDETTV-- 122

  Fly   158 LNDSDNEELQKELQLDDFSSYFERSYEPKVLITFADNPVTKTRKFGLELSRIFPNALVKIRNKSS 222
              :.::||:..:...|:||:||.|...||||||.:|.|..:|.:|..:|:.:.|:|.|..|...:
Zfish   123 --NPEDEEVAFDEGTDEFSAYFNRLTNPKVLITTSDRPRGRTVRFCDQLATVIPHAYVYYRRGLA 185

  Fly   223 VKKICKSAEREEFTDVVIVNEDRRKPNGLLVIHLPNGPTAHFKLSNVKLTSDIKRDHKEITKHRP 287
            :||:........||.::::||||:.|||:::.|||:|||||||:|:|:|..::||..|..|:|.|
Zfish   186 LKKVIPQCISRGFTYLMVINEDRKVPNGMVLCHLPDGPTAHFKVSSVRLRKEMKRRGKNPTEHSP 250

  Fly   288 EVILNNFTTRLGLTVGRMLGALFHHDPEFRGRRAVTFHNQRDYIFFRHHRYEFTKEGKRVKLREL 352
            ||||||||||||.::||:..|||.|||:|.||:..|||||||:||||.|||.|..| |:|.::||
Zfish   251 EVILNNFTTRLGHSIGRLFAALFPHDPQFVGRQVATFHNQRDFIFFRFHRYIFKNE-KKVGIQEL 314

  Fly   353 GPRFTLKLRSLQEGTFDSKTGDYAWIISNKRHAMESRRRFF 393
            ||||||||||||:||||||.|:|.|:  :|||.|:|.||.|
Zfish   315 GPRFTLKLRSLQKGTFDSKFGEYEWV--HKRHEMDSSRRKF 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6712	NP_477479.1	Brix	188..358	CDD:214879	89/169 (53%)
rpf1	NP_001002160.2	Brix	151..320	CDD:214879	89/169 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581703
Domainoid	1	1.000	185	1.000	Domainoid score	I3325
eggNOG	1	0.900	-	-		E1_COG2136
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68728
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2864
OMA	1	1.010	-	-		QHG53520
OrthoDB	1	1.010	-	-		D768872at2759
OrthoFinder	1	1.000	-	-		FOG0004778
OrthoInspector	1	1.000	-	-		oto41076
orthoMCL	1	0.900	-	-		OOG6_102467
Panther	1	1.100	-	-	LDO	PTHR22734
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3362
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770