Protein Alignment Pex19 and Pex19

DIOPT Version :10

• Sequence 1: NP_609547.2
• Gene: Pex19 / 34630
• FlyBaseID: FBgn0032407
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_075528.3
• Gene: Pex19 / 19298
• MGIID: 1334458
• Length: 299
• Species: Mus musculus
• Alignment Length: 301
• Identity: 91/301 - (30%)
• Similarity: 150/301 - (49%)
• Gaps: 36/301 - (11%)

  Fly    10 ELNDLLDSALQDFDKSGAGDQKEPSASSDVATNAGPE----GSEDPDAFFIEQAKVLADRMNTLF 70
            ||.:||:|||.||||:....:..|:.|:..|  :||:    |....||.|..|.|...:..::..
Mouse    17 ELEELLESALDDFDKAKPSPEHAPTISAPDA--SGPQKRAPGDTAKDALFASQEKFFQELFDSEL 79

  Fly    71 GGPDTPSGD--IPPLPQDPDQIMAGFKKMAEAAALTLSGENSATDEDVSKYSDSISQALKGLQEG 133
            ....|...:  :..|.::...::..|:|::|||...  |.::::.::   ::..:.:.|.||.:.
Mouse    80 ASQATAEFEKAMKELAEEEPHLVEQFQKLSEAAGRV--GSDASSQQE---FTSCLKETLSGLAKN 139

  Fly   134 SENLA-APASENDIASMFGSLNLEGAG--EGDGN-MFLPFMEGMMQSLLSAEILLPSIRELLEKY 194
            :..|. :..||.::...     :||.|  ||||. ..||.|:.:||:|||.::|.||::|:.|||
Mouse   140 ATELQNSGMSEEELMKA-----MEGLGMDEGDGEASILPIMQSIMQNLLSKDVLYPSLKEITEKY 199

  Fly   195 PKYLEENDAKLSAEDKERYQKQMELYKVIEGHLQSEKTEDSAAVKREKFRVVLDDMRKLQDYGQP 259
            |::|:.:......|..|:||:|..:...|....::|...||.|.:|.:|..:||.|::||..|.|
Mouse   200 PEWLQSHQDSTPPEQFEKYQQQHSVMVKICEQFEAETPTDSEATQRARFEAMLDLMQQLQALGHP 264

  Fly   260 PPEILAETGGDLPF--------GDPTAGVAAGGPGPQCPTM 292
            |.|:..|....|.|        |.|      |..|.||..|
Mouse   265 PKELAGEMPPGLNFDLDALNLSGPP------GANGEQCLIM 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pex19	NP_609547.2	Pex19	50..292	CDD:461367	73/255 (29%)
Pex19	NP_075528.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..61		18/47 (38%)
		Necessary for PEX19 function on peroxisome biogenesis. /evidence=ECO:0000250	2..91		23/79 (29%)
		Docking to the peroxisome membrane and binding to PEX3. /evidence=ECO:0000250	2..56		17/42 (40%)
		Pex19	74..299	CDD:461367	68/238 (29%)