Protein Alignment prd and ISX

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001290437.1
• Gene: ISX / 91464
• HGNCID: 28084
• Length: 245
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 73/235 - (31%)
• Similarity: 108/235 - (45%)
• Gaps: 55/235 - (23%)

  Fly   133 GVCDR----STAPSVSAISRLVRGRDAPLDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKP 193
            |.|:.    |.:.|:.||.:....|     :||....| |..:|...:::.||.:.       ||
Human    19 GCCEAPKKLSLSFSIEAILKRPARR-----SDMDRPEG-PGEEGPGEAAASGSGLE-------KP 70

  Fly   194 SDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQ 258
            ..:     :.:.|   ::.:||.||||:..||.|||:.|..|.|||::.|.:||.|.||.|||:|
Human    71 PKD-----QPQEG---RKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQ 127

  Fly   259 VWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSL----PSVVS-SVPSMAPLAMMPGSLDP 318
            :||.|:||:.|||....:.|||  ...|.:.||..::|    |:..| ::..:||    |.|..|
Human   128 IWFQNQRAKWRKQEKIGNLGAP--QQLSEASVALPTNLDVAGPTWTSTALRRLAP----PTSCCP 186

  Fly   319 ATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPH 358
                               ||...:||:.....||..|.|
Human   187 -------------------SAQDQLASAWFPAWITLLPAH 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	6/24 (25%)
		Homeodomain	214..270	CDD:459649	31/55 (56%)
ISX	NP_001290437.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..86		13/68 (19%)
		Homeodomain	83..139	CDD:459649	31/55 (56%)