Protein Alignment prd and RHOXF2B

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001093155.1
• Gene: RHOXF2B / 727940
• HGNCID: 33519
• Length: 288
• Species: Homo sapiens
• Alignment Length: 307
• Identity: 73/307 - (23%)
• Similarity: 110/307 - (35%)
• Gaps: 80/307 - (26%)

  Fly   129 LIREGVCDRSTAPSVSA--ISRLVRGRDAPLDNDMSSASGSPAGDGTKASSSCGSDV--SGGHHN 189
            |:...|.|......::|  :|.....::...|.......|:.||:..|::.:.|.:.  .||...
Human    14 LLSPAVDDEKELQDMNAMVLSLTEEVKEEEEDAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEK 78

  Fly   190 NG-----------------KPSD---EDISDCESEPGIALKRKQRRCR------------TTFSA 222
            :|                 ..||   ||....|.|||....|.|....            ..|:.
Human    79 DGGGAGVPGHLWEGNLEGTSGSDGNVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTP 143

  Fly   223 SQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLRKQHTSVSGGAPGGAAASV 287
            .||.|||..|:|.|:|..:.|..||:..|:||..:|:||.||||:.|:...:
Human   144 LQLQELECIFQREQFPSEFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRA------------- 195

  Fly   288 SHVAASSSLPSVVSSVPSMAPLAMMPGSLDPATVYQQQYDFYGSHANISVSAAAPMASSNLSPGI 352
              :.|.:.||.:....|.|...|  .....|..:...:.|::..|:: |.|...||
Human   196 --LMARNMLPFMAVGQPVMVTAA--EAITAPLFISGMRDDYFWDHSH-SSSLCFPM--------- 246

  Fly   353 TTTPPHHHQFYNPSANTASYIMP-------GENGNTTPTGNIIVSSY 392
               ||    |..||......::|       .|.|   |...:||.|:
Human   247 ---PP----FPPPSLPLPLMLLPPMPPAGQAEFG---PFPFVIVPSF 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	5/26 (19%)
		Homeodomain	214..270	CDD:459649	23/67 (34%)
RHOXF2B	NP_001093155.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..136		23/119 (19%)
		Homeodomain	139..191	CDD:459649	23/51 (45%)
		PRK02287	<183..>232	CDD:235024	12/65 (18%)
		Nuclear localization signal. /evidence=ECO:0000250	186..195		3/8 (38%)