Protein Alignment prd and SHOX2

DIOPT Version :9

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_003021.3
• Gene: SHOX2 / 6474
• HGNCID: 10854
• Length: 355
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 105/420 - (25%)
• Similarity: 149/420 - (35%)
• Gaps: 145/420 - (34%)

  Fly   121 FSWEIREKLIREGVCDRSTAPSVSAISRLVRGRDAPLD------NDMSS-----ASGSPAGDGTK 174
            |..:::||  :|.:..|....|..     :||...|..      :|.||     |.|...|.|..
Human    12 FDQKVKEK--KEAITYREVLESGP-----LRGAKEPTGCTEAGRDDRSSPAVRAAGGGGGGGGGG 69

  Fly   175 ASSSCGSDVSGGHHNNG--------------------------------KPSDEDISDCESEPGI 207
            .....|..|.||....|                                ||:..::......||.
Human    70 GGGGGGGGVGGGGAGGGAGGGRSPVRELDMGAAERSREPGSPRLTEGRRKPTKAEVQATLLLPGE 134

  Fly   208 AL------------------------KRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQ 248
            |.                        |.||||.||.|:..||:||||.|:.|.|||.:.||||:|
Human   135 AFRFLVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQ 199

  Fly   249 RTNLTEARIQVWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMP 313
            |..|:|||:||||.||||:.|||...:..|...|||   |...|....|.|  :|.::    .||
Human   200 RLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAA---SQFEACRVAPYV--NVGAL----RMP 255

  Fly   314 GSLDPATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIMPGEN 378
                    :||.     ||.|::..:....|...|...:...  |||...:.:|:....:.|
Human   256 --------FQQD-----SHCNVTPLSFQVQAQLQLDSAVAHA--HHHLHPHLAAHAPYMMFP--- 302

  Fly   379 GNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGV 443
              ..|.|                        :|......:|.|:|            :||:.|..
Human   303 --APPFG------------------------LPLATLAADSASAA------------SVVAAAAA 329

  Fly   444 TSSSGANSGADPSQSLANASAGSEELSAAL 473
            ..::..||      |:|:....:::.:|||
Human   330 AKTTSKNS------SIADLRLKAKKHAAAL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	8/32 (25%)
		Homeobox	217..269	CDD:278475	32/51 (63%)
SHOX2	NP_003021.3	Homeobox	167..220	CDD:306543	32/52 (62%)
		OAR	335..351	CDD:309087	4/21 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910