DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prd and mxtx2

DIOPT Version :9

Sequence 1:	NP_723721.1	Gene:	prd / 34629	FlyBaseID:	FBgn0003145	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001073284.1	Gene:	mxtx2 / 58078	ZFINID:	ZDB-GENE-000710-6	Length:	296	Species:	Danio rerio

Alignment Length:	355	Identity:	90/355 - (25%)
Similarity:	127/355 - (35%)	Gaps:	103/355 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 SDCESEPG--IALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWF 261
            :||.::.|  .|.|...||.||:|:...|:.|:.||....||.|..||.|:|.|.|.|:||||||
Zfish     6 TDCIAQDGNSQASKIAGRRKRTSFTKEHLELLKMAFNVDPYPGISVRESLSQATGLPESRIQVWF 70

  Fly   262 SNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPATVYQQQY 326
            .|:|||..|..                   |..|.|.:.:..|..:|  .:|..:....|..||.
Zfish    71 QNKRARTLKNR-------------------AIQSSPQLDNKSPLPSP--FLPPHMASVGVSAQQR 114

  Fly   327 DFYGSHANISVSAAAP----------------------MASSNLSPG-ITTTPPHHHQFYNPSAN 368
            ....|..||.:|..:|                      |.:|:.||. :..||.......:...:
Zfish   115 GIQESPFNIQMSQTSPQHFTFPPSDYSTPVVKPRQTRLMGTSSCSPSDLQATPDSWSYAGSTQIS 179

  Fly   369 TASYIMPGEN-GNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPN 432
            ..|:.:..|| ||          ||                   ::|||       |...||.|.
Zfish   180 PESWDVAAENFGN----------SY-------------------KDESP-------FFLYPPPPY 208

  Fly   433 SLSAVVSGAGVTSSSGANSGADPSQSLANASAGSEELSAALKVESVDLIAASQSQLYGGWSSMQA 497
            ...:  :..|..||..:.|.:..|...|....|.|..|.::...|..          ..|..:..
Zfish   209 PYGS--TRVGCPSSMESLSTSPASSDSAFWDMGLENCSPSVPYTSCG----------SPWDRLTE 261

  Fly   498 LRPNAPLSPEDSLNSTSSTSQALDVTAHQM 527
            .:|.||| |:.|       ||.|:....:|
Zfish   262 EQPVAPL-PDLS-------SQCLEDVLGEM 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076
prd	NP_723721.1	Homeobox	217..269	CDD:278475	27/51 (53%)
mxtx2	NP_001073284.1	HOX	22..76	CDD:197696	27/53 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810