Protein Alignment prd and otx2

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_012823826.1
• Gene: otx2 / 548931
• XenbaseID: XB-GENE-485220
• Length: 306
• Species: Xenopus tropicalis
• Alignment Length: 363
• Identity: 75/363 - (20%)
• Similarity: 113/363 - (31%)
• Gaps: 107/363 - (29%)

  Fly   128 EKPRITGPTPAPSPYPVPRIPGVVPVRLAVDPNNHVNDGQSEQHHSHQYYKIGQQLYKVQQEHGV 192
            |.|:......|.|......|..:|....||..|  ::|...::......|:|...:.||::  ..
 Frog   775 EDPKFREAVKAASDELSKTISPMVMDAKAVAGN--ISDPGLQKSFLDSGYRILGAVAKVRE--AF 835

  Fly   193 TPTKLQTVPPPPPRQHLTETILTQHATPQKPAEVAGKSPPTGQYYLTPNYKVYKVPAKHHHTVPE 257
            .|.:....||||..:.|.   ||....|.||....|:.||...          ..|.:.....||
 Frog   836 QPQEPDFPPPPPDLEQLR---LTDELAPPKPPLPEGEVPPPRP----------PPPEEKDEEFPE 887

  Fly   258 HPAYQYAHPQPVAV-----------YSSTTPRPVSYSSVSPSTTPAPVHETPSYPVYHPSVKPPR 311
            ..|.:..: ||:.:           :||....|.:...:. ....|...:...:||      ||
 Frog   888 QKAGEVIN-QPMMMAARQLHDEARKWSSKPGIPAAEVGIG-VVAEADAADAAGFPV------PP- 943

  Fly   312 HNRTEYANRQRFYPQSMRHPS-QHKPRPIPLAPAPVDHEQALGFPA------APAPGSSL----- 364
                  .....:.|:.:..|| |...:|| ||.|...|.:|..:.:      |.|...:|
 Frog   944 ------DMEDDYEPELLLMPSNQPVNQPI-LAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEM 1001

  Fly   365 ------------------ADLLKNLQDNNLLPKTLTPDNIDNSIR--------------TLVKIL 397
                              .|:.|...:...|.|.:.....|..||              |.:|||
 Frog  1002 SRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKIL 1066

  Fly   398 NNLKANGHPQRPPVAEPPETPREPTTYERTNYTTVEPE 435
            :.:||                   |...|||.:..|.|
 Frog  1067 STVKA-------------------TMLGRTNISDEESE 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	6/25 (24%)
		Homeodomain	214..270	CDD:459649	14/55 (25%)
otx2	XP_012823826.1	Homeodomain	56..111	CDD:459649
		TF_Otx	170..251	CDD:427350