Protein Alignment prd and PRRX1

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_073207.1
• Gene: PRRX1 / 5396
• HGNCID: 9142
• Length: 245
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 74/221 - (33%)
• Similarity: 99/221 - (44%)
• Gaps: 17/221 - (7%)

  Fly   128 KLIREGVCDRSTAPSVSAISRLVRGRDAPLDNDMSSASGSPAGDGTKASSSCGSDV--SGGHHNN 190
            :|...|..|...|....::|.|:         |:..|....|....:.....|..:  |.|..:.
Human    18 RLDSPGNLDTLQAKKNFSVSHLL---------DLEEAGDMVAAQADENVGEAGRSLLESPGLTSG 73

  Fly   191 GKPSDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEA 255
            .....:|.....||.  ..||||||.||||::|||..|||.||||.|||.:.||:||:|.|||||
Human    74 SDTPQQDNDQLNSEE--KKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEA 136

  Fly   256 RIQVWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPAT 320
            |:||||.||||:.|:...::..........|.|....:...|    .||..||......|...|:
Human   137 RVQVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQP----IVPRPAPRPTDYLSWGTAS 197

  Fly   321 VYQQQYDFYGSHANISVSAAAPMASS 346
            .|.....:..:.||.|.:....||:|
Human   198 PYSAMATYSATCANNSPAQGINMANS 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	6/25 (24%)
		Homeodomain	214..270	CDD:459649	38/55 (69%)
PRRX1	NP_073207.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22		1/3 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..103		15/41 (37%)
		Homeodomain	99..151	CDD:459649	35/51 (69%)
		OAR	219..235	CDD:461067	3/5 (60%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	222..235		1/2 (50%)