Protein Alignment prd and PRRX2

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_057391.1
• Gene: PRRX2 / 51450
• HGNCID: 21338
• Length: 253
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 79/238 - (33%)
• Similarity: 110/238 - (46%)
• Gaps: 60/238 - (25%)

  Fly   157 LDNDMSSASGSPA---GDGTKASSSCGSDVSGGHHNNGKPSDEDISDCESEPG----IALKRKQR 214
            ||.:..:|:|..|   |...:|......:.|||  ::|..:.....:|.| ||    ...|:|||
Human    44 LDLEEVAAAGRLAARPGARAEAREGAAREPSGG--SSGSEAAPQDGECPS-PGRGSAAKRKKKQR 105

  Fly   215 RCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLRKQHTSVSGGA 279
            |.||||::|||..|||.||||.|||.:.|||||:|.||:|||:||||.||||:.|:...::....
Human   106 RNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFRRNERAMLASR 170

  Fly   280 PGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPATVYQQQYDFYGSHANISVSAAAPMA 344
            ......|.|..||...            |:|..|.:|.|        |:      :|.:|::|
Human   171 SASLLKSYSQEAAIEQ------------PVAPRPTALSP--------DY------LSWTASSP-- 207

  Fly   345 SSNLSPGITTTPPHHHQFYNPSANTASYIMPGENGNTTPTGNI 387
                   .:|.||:               .||.:|..||..|:
Human   208 -------YSTVPPY---------------SPGSSGPATPGVNM 228

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076
		Homeodomain	214..270	CDD:459649	38/55 (69%)
PRRX2	NP_057391.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	55..113		20/60 (33%)
		Homeodomain	109..161	CDD:459649	35/51 (69%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	230..243