Protein Alignment prd and ARGFX

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001012677.1
• Gene: ARGFX / 503582
• HGNCID: 30146
• Length: 315
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 82/356 - (23%)
• Similarity: 142/356 - (39%)
• Gaps: 91/356 - (25%)

  Fly   140 APSVSAISRLVRGRDAPLDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKPSDEDISDCESE 204
            :||.:.:|:|             ..||:       .|:.|..::.|.       :|...|.....
Human    33 SPSFTLLSKL-------------ECSGT-------VSAYCSLNLPGS-------TDPPTSASRVA 70

  Fly   205 PGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLR 269
            ...|::|:.:. ||:|:..|.:|||..|.:|.:||...:|:||.|.:|.|:.::|||.|||.:|:
Human    71 ATTAIRRRHKE-RTSFTHQQYEELEALFSQTMFPDRNLQEKLALRLDLPESTVKVWFRNRRFKLK 134

  Fly   270 KQHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPATVYQQQYDFYGSHAN 334
            ||....|.            ...:..||| ..:||:....:..|.:..|..     .|||.|
Human   135 KQQQQQSA------------KQRNQILPS-KKNVPTSPRTSPSPYAFSPVI-----SDFYSS--- 178

  Fly   335 ISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIMPGENGNTTPTGNIIVS-------SY 392
               ..:.|:..||.:...|.|          .::|:.:.|     ..|....::.|       :|
Human   179 ---LPSQPLDPSNWAWNSTFT----------ESSTSDFQM-----QDTQWERLVASVPALYSDAY 225

  Fly   393 ET-QLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGVTSSSGANSGADPS 456
            :. |:..:|....|       ||..:.|....:..|.||...:..  .|:.::..:|...|..|:
Human   226 DIFQIIELYNLPDE-------NEISSSSFHCLYQYLSPTKYQVGG--QGSSLSIFAGPAVGLSPA 281

  Fly   457 QSLANASAGSEE---LSAALKVES----VDL 480
            |:..|.::.:.|   |:.:|:.:.    |||
Human   282 QTWPNMTSQAFEAYSLTDSLEFQKTSNMVDL 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	4/13 (31%)
		Homeodomain	214..270	CDD:459649	24/55 (44%)
ARGFX	NP_001012677.1	Homeodomain	80..130	CDD:459649	21/50 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	135..163		8/40 (20%)