Protein Alignment prd and Pax5

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_038966491.1
• Gene: Pax5 / 500453
• RGDID: 1565236
• Length: 410
• Species: Rattus norvegicus
• Alignment Length: 467
• Identity: 169/467 - (36%)
• Similarity: 233/467 - (49%)
• Gaps: 91/467 - (19%)

  Fly    18 YSTMQDMNSGQGRVNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNR 82
            |.|.:.:.:|.|.||||||||:||||||:.:|.:|||:|..|:|||.||||||||||||||||.|
  Rat     7 YPTPRTIRTGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGR 71

  Fly    83 YQETGSIRPGVIGGSKPRIATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAPSVSAIS 147
            |.|||||:|||||||||::|||::..:|.||||.:|.||:||||::|:.|.|||..|.||||:|:
  Rat    72 YYETGSIKPGVIGGSKPKVATPKVVEKIAEYKRQNPTMFAWEIRDRLLAERVCDNDTVPSVSSIN 136

  Fly   148 RLVRGR-DAPLDNDMSSASGSPAGDGTKAS-SSCGSDVSGGHHN--------------NGKPSDE 196
            |::|.: ..|.:..:.::|.|....|:... ||..:|.:|..::              |.:..||
  Rat   137 RIIRTKVQQPPNQPVPASSHSIVSTGSVTQVSSVSTDSAGSSYSISGILGITSPSADTNKRKRDE 201

  Fly   197 DISDC-----ESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEAR 256
            .|.:.     .|.||....|||.| ...|:..||:.|:|.|||..|.||:|..|..:........
  Rat   202 GIQESPVPNGHSLPGRDFLRKQMR-GDLFTQQQLEVLDRVFERQHYSDIFTTTEPIKPEQWCPVL 265

  Fly   257 IQVWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSLPS---VVSSVPSMAPLAMMPGSLDP 318
            ::.:.:..:|.| .|.|..|  |....|.|:..:.|:.:.|:   :.||||.
  Rat   266 MRQYLAQPQAVL-FQTTEYS--AMASLAGSLDDMKANLTSPTPADIGSSVPG------------- 314

  Fly   319 ATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIMPGENGNTTP 383
                .|.|         .:.....:||:.| ||.   |||     .|.|...||..|      |.
  Rat   315 ----PQSY---------PIVTGRDLASTTL-PGY---PPH-----VPPAGQGSYSAP------TL 351

  Fly   384 TGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGVTSSSG 448
            ||.:..|.:.   ||.|     :|   |:..|.|:|...      |.|..|     |:....|:.
  Rat   352 TGMVPGSEFS---GSPY-----SH---PQYSSYNDSWRF------PNPGLL-----GSPYYYSAA 394

  Fly   449 ANSGADPSQSLA 460
            |...|.|:.:.|
  Rat   395 ARGAAPPAAATA 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	85/127 (67%)
		Homeodomain	214..270	CDD:459649	16/55 (29%)
Pax5	XP_038966491.1	PAX	16..140	CDD:128645	84/123 (68%)
		Pax2_C	298..409	CDD:463563	42/172 (24%)