Protein Alignment prd and Phox2b

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001414175.1
• Gene: Phox2b / 364152
• RGDID: 1560582
• Length: 314
• Species: Rattus norvegicus
• Alignment Length: 277
• Identity: 82/277 - (29%)
• Similarity: 109/277 - (39%)
• Gaps: 105/277 - (37%)

  Fly   144 SAISRLVRGRD----APLDNDMSS---ASG---SPAGDGTKASSSCGSDVSGGHHNNGKPSDEDI 198
            ||....:.|.|    |....|.||   |||   :|......|:|.|.| ::.|..:.|...|...
  Rat    12 SAYESCMAGMDTSSLASAYADFSSCSQASGFQYNPIRTTFGATSGCPS-LTPGSCSLGTLRDHQS 75

  Fly   199 SDCESEP--------GIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEA 255
            |...:.|        |:..||||||.||||:::||.||||.|..|.|||||||||||.:.:||||
  Rat    76 SPYAAVPYKLFTDHGGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEA 140

  Fly   256 RIQVWFSNRRARLRKQHTSVS-------------------------------------------- 276
            |:||||.||||:.|||..:.:
  Rat   141 RVQVWFQNRRAKFRKQERAAAAAAAAAKNGSSGKKSDSSRDDESKEAKSTDPDSTGGPGPNPNPT 205

  Fly   277 ---------GGAP--------------------GGAAASVSHVAASSSLPSVVSS---------- 302
                     ||.|                    |||||:.:..||:::..:..::
  Rat   206 PSCGANGGGGGGPSPAGAPGAAGPGGPGGEPGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAGGPG 270

  Fly   303 ---VPSMAPLAMMPGSL 316
               .|...|:..:|.||
  Rat   271 QGWAPGPGPITSIPDSL 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	3/9 (33%)
		Homeodomain	214..270	CDD:459649	38/55 (69%)
Phox2b	NP_001414175.1	Homeodomain	99..155	CDD:459649	38/55 (69%)