DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prd and sdcbp2

DIOPT Version :9

Sequence 1:	NP_723721.1	Gene:	prd / 34629	FlyBaseID:	FBgn0003145	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_997856.1	Gene:	sdcbp2 / 325004	ZFINID:	ZDB-GENE-030131-3727	Length:	299	Species:	Danio rerio

Alignment Length:	232	Identity:	44/232 - (18%)
Similarity:	67/232 - (28%)	Gaps:	91/232 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   344 ASSNLSPGITTTPPHHHQFYNPSANTASYIMPGENGNTTPTGNIIVSSYETQLGSVYGTETETHQ 408
            |.|..:...::||......|.|...|..  ||    ::|...|:      .:||...|....:.:
Zfish    18 AQSQFANATSSTPAITQGAYQPQPATQG--MP----SSTLYPNL------EELGDYMGLSLNSDE 70

  Fly   409 TMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGVTSSSGAN----SGADPSQSLANASAGSEEL 469
             :.||                  .:|..|.:...|.||.|..    :|||.....|....|..|:
Zfish    71 -VQRN------------------LALVPVATQVAVPSSVGGMVRPVTGADMGIRRAEIRPGLREV 116

  Fly   470 --------SAALKVESVD------LIAAS-----------------QSQLYGGWSSMQALRPNAP 503
                    ...|::..:|      |:.|:                 ..|...||:|.:|
Zfish   117 ILCKDQEGKVGLRLRDIDNGVFVQLVQANSPAALAGLRFGDQVLQINGQNVAGWNSDKA------ 175

  Fly   504 LSPEDSLNSTSSTSQALDVTAHQMF------HPYQHT 534
                         .:||...|.|..      .|:|.|
Zfish   176 -------------HKALKAAAEQRIELIVRDRPFQRT 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076
prd	NP_723721.1	Homeobox	217..269	CDD:278475
sdcbp2	NP_997856.1	PDZ_signaling	113..>173	CDD:238492	8/59 (14%)
sdcbp2	NP_997856.1	PDZ_signaling	198..270	CDD:238492	1/2 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900