DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment prd and oc

DIOPT Version :9

Sequence 1:	NP_723721.1	Gene:	prd / 34629	FlyBaseID:	FBgn0003145	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001356934.1	Gene:	oc / 31802	FlyBaseID:	FBgn0004102	Length:	664	Species:	Drosophila melanogaster

Alignment Length:	508	Identity:	140/508 - (27%)
Similarity:	201/508 - (39%)	Gaps:	143/508 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 RKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLRKQ---- 271
            |||||.||||:.:|||.||..|.:|:||||:.|||:|.:.||.|:|:||||.||||:.|:|
  Fly    65 RKQRRERTTFTRAQLDVLEALFGKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKCRQQLQQQ 129

  Fly   272 --------HTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPATVYQQQYDF 328
                    ..:.|||..|.:.:|.|..:.|:|..:..||..:    ....|..:.....|:|.:.
  Fly   130 QQSNSLSSSKNASGGGSGNSCSSSSANSRSNSNNNGSSSNNN----TQSSGGNNSNKSSQKQGNS 190

  Fly   329 Y----------GSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIMPGEN----- 378
            .          |:::|.:.:|||..|::.:: ...:...||..|.:.:|..||   .|.|
  Fly   191 QSSQQGGGSSGGNNSNNNSAAAAASAAAAVA-AAQSIKTHHSSFLSAAAAAAS---GGTNQSANN 251

  Fly   379 -------GNTTPTGNIIVSSYETQLGSVYGTE--------TETHQTMPRNESPNESVSSAFGQLP 428
                   ||:||..:.......:|.|......        |..||    |.||          |.
  Fly   252 NSNNNNQGNSTPNSSSSGGGGGSQAGGHLSAAAAAAALNVTAAHQ----NSSP----------LL 302

  Fly   429 PTP-NSLSAV--------VSGAGVTSSSGANSGADPSQSLANASAGSEELSAALKV-------ES 477
            ||| .|:|.|        :|| |..||.|...|.      ..||:|...|...:.|       .|
  Fly   303 PTPATSVSPVSIVCKKEHLSG-GYGSSVGGGGGG------GGASSGGLNLGVGVGVGVGVGVGVS 360

  Fly   478 VDLIAASQSQL-----------------YG--GWSSMQALRPNAPLSPEDSLNSTSSTSQALDVT 523
            .||:.:...||                 ||  ..|:.:.|:|...::|.||.:|.::.|..:...
  Fly   361 QDLLRSPYDQLKDAGGDIGAGVHHHHSIYGSAAGSNPRLLQPGGNITPMDSSSSITTPSPPITPM 425

  Fly   524 AHQMFHPYQHTPQYASYPAPGHAH-----SHHGHPHAPHPHAHPHP-QYAGAHPHYPPPSSSAHF 582
            :.|......|..|.|.......||     |:|...:..|.....:| .||.|..:|   |...:|
  Fly   426 SPQSAAAAAHAAQSAQSAHHSAAHSAAYMSNHDSYNFWHNQYQQYPNNYAQAPSYY---SQMEYF 487

  Fly   583 MPQN----------FNAAAF---PSPS-------------KVNYTTMPPQPFY 609
            ..||          :.|:.|   ||||             .::|  |.||..|
  Fly   488 SNQNQVNYNMGHSGYTASNFGLSPSPSFTGTVSAQAFSQNSLDY--MSPQDKY 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076
prd	NP_723721.1	Homeobox	217..269	CDD:278475	31/51 (61%)
oc	NP_001356934.1	Homeobox	71..123	CDD:333795	31/51 (61%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450999
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840