DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prd and Vsx2

DIOPT Version :9

Sequence 1:	NP_723721.1	Gene:	prd / 34629	FlyBaseID:	FBgn0003145	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001284897.1	Gene:	Vsx2 / 31469	FlyBaseID:	FBgn0263512	Length:	645	Species:	Drosophila melanogaster

Alignment Length:	447	Identity:	110/447 - (24%)
Similarity:	158/447 - (35%)	Gaps:	156/447 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 GRDAPLDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKPSDEDISDCESEPGIALKRKQRRC 216
            |..||.|..|.|.:|...|..:|..                                 |:|:|..
  Fly   202 GSLAPKDFGMESLNGFGVGPNSKKK---------------------------------KKKRRHS 233

  Fly   217 RTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLRKQHTSVSGGAP- 280
            ||.|::.||::||.||:...|||:|.||.|:.:|.|.|.||||||.||||:.||.. .|.||:.
  Fly   234 RTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTE-KVWGGSTI 297

  Fly   281 ----GGAAASVSHVAASSSLP---SVVSSV---PSMAP--LAMMPGSLDPATVYQQ--------- 324
                |...|.|.|     |||   :::.|.   .::||  |.|....:...::..|
  Fly   298 MAEYGLYGAMVRH-----SLPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGV 357

  Fly   325 --QYDFYGS-------------HA----NISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTA 370
              ..|..||             ||    ..|::..:|..||..:...|:.||         .:|:
  Fly   358 SDHEDSAGSKSAHSEDLSRSRCHALSSSTESLNVVSPAPSSCPTSASTSAPP---------TSTS 413

  Fly   371 SYIMPGENGNTTPTGNIIV---SSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQL----- 427
            .|.....:..|||||....   ||...:|||. ..:.:.|..:.:.:....|:....|.:
  Fly   414 GYAGAASSAATTPTGASTTNSSSSPHIELGSP-SPQQQQHLQLQQQQQQQASLYLGAGAVVTGCA 477

  Fly   428 PPTPNSLSAVVSGAGVTSSSGANSGADPSQSLANASAGSEELSAALKVESVDLIAASQSQLYGGW 492
            ||:.:.|....:.||                 |.|:|.|::....:........||:|.|
  Fly   478 PPSYHPLLDAANAAG-----------------AGAAASSKDFHMIMNTAVAAAAAAAQQQ----- 520

  Fly   493 SSMQALRPNAPLSPEDSLNSTSSTSQALDVTAHQMFHPYQHTPQYASYPAPG-HAHS 548
                                            ||.   .|...|.|:..||| |||:
  Fly   521 --------------------------------HQQ---QQQQQQQATATAPGLHAHN 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	1/1 (100%)
prd	NP_723721.1	Homeobox	217..269	CDD:278475	29/51 (57%)
Vsx2	NP_001284897.1	Homeobox	233..286	CDD:278475	29/52 (56%)
Vsx2	NP_001284897.1	OAR	556..570	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45450957
Domainoid	1	1.000	55	1.000	Domainoid score	I4097
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840