Protein Alignment prd and pax3a

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_571352.1
• Gene: pax3a / 30532
• ZFINID: ZDB-GENE-980526-52
• Length: 509
• Species: Danio rerio
• Alignment Length: 524
• Identity: 225/524 - (42%)
• Similarity: 278/524 - (53%)
• Gaps: 94/524 - (17%)

  Fly     3 VTAFAAAMHR-----PFFN----GYSTMQDMNSGQGRVNQLGGVFINGRPLPNNIRLKIVEMAAD 58
            :||.|..:.|     |..|    |||.......||||||||||||||||||||:||.||||||..
Zfish     1 MTALAGGISRMMRPTPPQNYPRGGYSLEVSTPLGQGRVNQLGGVFINGRPLPNHIRHKIVEMAHH 65

  Fly    59 GIRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPR-IATPEIENRIEEYKRSSPGMFS 122
            ||||||||||||||||||||||.|||||||||||.||||||: ..||::|.:||||||.:|||||
Zfish    66 GIRPCVISRQLRVSHGCVSKILCRYQETGSIRPGAIGGSKPKQSTTPDVEKKIEEYKRENPGMFS 130

  Fly   123 WEIREKLIREGVCDRSTAPSVSAISRLVR---GRDAPLDNDMSSASGSPAGDGTKASSSCGSDVS 184
            ||||:||:::|:|||:..||||:|||::|   |.:...|.|..........:..:.:......:.
Zfish   131 WEIRDKLLKDGICDRNNVPSVSSISRMLRCKFGGNGDEDEDDDEVEKREIEENERRAKHSIDGIL 195

  Fly   185 GGHHNNGKPSDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQR 249
            |...::   |||. ||.:||||:.|||||||.||||:|.||:|||||||||.|||||||||||||
Zfish   196 GDRSSH---SDEG-SDVDSEPGLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQR 256

  Fly   250 TNLTEARIQVWFSNRRARLRKQ---------HTSVSGGAPGGAAASVS--HVAASSSLPSVVSSV 303
            ..|||||:||||||||||.|||         :..:.||.|..|.:|:.  .:|.|...||.:|.|
Zfish   257 AKLTEARVQVWFSNRRARWRKQAGANQLMAFNHLIPGGFPPSAMSSLQPYQLADSPYPPSSISQV 321

  Fly   304 PSMAPLAMMPGSLDPATVYQQQYDFYGSHANISVSAAAPMAS------SNLSPGITTTPPHHHQF 362
            .........|..|.|.:|:|..   .||.......::|...|      |..|.|....|.|.:.
Zfish   322 SEQPSTVHRPQPLPPTSVHQSG---LGSGPGAQEGSSAYCLSSGRHGFSGYSDGYVAAPGHANP- 382

  Fly   363 YNPSANTA--SYIMPGENGNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFG 425
            .|||.:..  |.:|    |...|                                         |
Zfish   383 VNPSISNGLPSQVM----GLLNP-----------------------------------------G 402

  Fly   426 QLPPTPNSLSAVVSGAGVTSSSGANSGADPSQSLANASAGSEELSAALKVESVDLIAASQSQLYG 490
            .:|..|.|..|:         |....|.:||..:..:...|:.|.|...:.|:..:.:|||....
Zfish   403 AVPHQPQSDFAL---------SPLTGGLEPSTGMPASCHSSQRLEALPGLPSMPALPSSQSYCPS 458

  Fly   491 GWSS 494
            .:||
Zfish   459 SYSS 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	100/130 (77%)
		Homeodomain	214..270	CDD:459649	46/55 (84%)
pax3a	NP_571352.1	PAX	34..159	CDD:128645	98/124 (79%)
		Homeodomain	221..277	CDD:459649	46/55 (84%)
		Pax7	350..394	CDD:403540	10/44 (23%)