DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prd and Pax2

DIOPT Version :9

Sequence 1:	NP_723721.1	Gene:	prd / 34629	FlyBaseID:	FBgn0003145	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_006231505.2	Gene:	Pax2 / 293992	RGDID:	1305568	Length:	432	Species:	Rattus norvegicus

Alignment Length:	470	Identity:	157/470 - (33%)
Similarity:	214/470 - (45%)	Gaps:	151/470 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 MNSGQGRVNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETGS 88
            |:.|.|.||||||||:||||||:.:|.:|||:|..|:|||.||||||||||||||||.||.||||
  Rat    13 MHPGHGGVNQLGGVFVNGRPLPDVVRQRIVELAHQGVRPCDISRQLRVSHGCVSKILGRYYETGS 77

  Fly    89 IRPGVIGGSKPRIATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAPSVSAISRLVR-- 151
            |:|||||||||::|||::.::|.||||.:|.||:||||::|:.||:||..|.||||:|:|::|
  Rat    78 IKPGVIGGSKPKVATPKVVDKIAEYKRQNPTMFAWEIRDRLLAEGICDNDTVPSVSSINRIIRTK 142

  Fly   152 --------------GRDAP--------LDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKP- 193
                          |..||        ....:||||..|.|      |...:.:.|...:||:.
  Rat   143 VQQPFHPTPDGAGTGVTAPGHTIVPSTASPPVSSASNDPVG------SYSINGILGIPRSNGEKR 201

  Fly   194 -----------------------------SDEDISDCESEPGIALKRKQRRCRTTFSASQLDELE 229
                                         |:..:.:.:|:.|:...||..|. .||:..||:.|:
  Rat   202 KREEVEVYTDPAHIRGGGGLHLVWTLRDVSEGSVPNGDSQSGVDSLRKHLRA-DTFTQQQLEALD 265

  Fly   230 RAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASS 294
            |.|||..|||::...|                                           |:.:..
  Rat   266 RVFERPSYPDVFQASE-------------------------------------------HIKSEQ 287

  Fly   295 ----SLPSVVSSVPSMAPLAMMPGSLDPATVYQQQYDFYGSHANISVSAAA-PMASSNLSPGITT 354
                |||            |:.|| ||              ....|:||:. |...||:| |..|
  Rat   288 GNEYSLP------------ALTPG-LD--------------EVKSSLSASTNPELGSNVS-GTQT 324

  Fly   355 TPPHHHQFYNPSANTASYIMPGENGNTTPTGNIIVSSYETQ--LGSVYGTE-TETHQTMPRNESP 416
            .|      .....:.||..:||...:..|||.   .||.|.  .|.|.|:| :....:.|:..:.
  Rat   325 YP------VVTGRDMASTTLPGYPPHVPPTGQ---GSYPTSTLAGMVPGSEFSGNPYSHPQYTAY 380

  Fly   417 NES--VSSAFGQLPP 429
            ||:  .|:....:||
  Rat   381 NEAWRFSNPALLMPP 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	86/142 (61%)
prd	NP_723721.1	Homeobox	217..269	CDD:278475	13/51 (25%)
Pax2	XP_006231505.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810