Protein Alignment prd and Pitx3

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_006526827.1
• Gene: Pitx3 / 18742
• MGIID: 1100498
• Length: 388
• Species: Mus musculus
• Alignment Length: 521
• Identity: 140/521 - (26%)
• Similarity: 184/521 - (35%)
• Gaps: 185/521 - (35%)

  Fly    63 CVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPRIATPEIENRIEEYKRSSPGMFSWEIRE 127
            ||.....|:|.|..|  ||.........|      .|...:.|||   :|.||..|....:
Mouse    40 CVWLHMCRLSLGAHS--LNSACHCSGCYP------LPGPPSTEIE---DEIKRQRPPSMEF---- 89

  Fly   128 KLIREGVCDRSTAPSVSAISRLVRGRDA-----PLDNDMSSASGSPAGDGTKASSSCGSDVSGGH 187
            .|:.|... ||.|.|:|         ||     ||..  ....|....|..|||:|    :.||.
Mouse    90 GLLGEAEA-RSPALSLS---------DAGTPHPPLPE--HGCKGQEHSDSEKASAS----LPGGS 138

  Fly   188 HNNGKPSDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNL 252
            ..:|                :||:||||.||.|::.||.|||..|:|.:|||:.||||:|..|||
Mouse   139 PEDG----------------SLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNL 187

  Fly   253 TEARIQVWFSNRRARLRKQHTSVSGG-APGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSL 316
            ||||::|||.||||:.||:..|.... ..||.|                      |||    |.|
Mouse   188 TEARVRVWFKNRRAKWRKRERSQQAELCKGGFA----------------------APL----GGL 226

  Fly   317 DPATVYQQQYDFYGSHANISVSAAAPMASSNLSP----GITTTPPHHHQFYNPSANTASYIMPGE 377
            .|.  |::.|..| |:.|....|.||..::...|    .:...|......::|.::.|:.::|
Mouse   227 VPP--YEEVYPGY-SYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVP-- 286

  Fly   378 NGNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAG 442
                                                     |.::|.|.:|           |.|
Mouse   287 -----------------------------------------SAAAAPGTVP-----------GPG 299

  Fly   443 VTSSSGANSGADPSQSLANASAGSEELSAALKVESVDLIAASQSQLYGGWSSMQALRPNAPLSPE 507
            .....|   ||.|  .||.|:..|..:|..                |...::..|...::|....
Mouse   300 ALQGLG---GAPP--GLAPAAVSSGAVSCP----------------YASAAAAAAAAASSPYVYR 343

  Fly   508 DSLNSTSSTSQALDVTAHQMFHPYQHTPQYASYPA-PGHAHSHHGHPHAPHPHAHPHP-QYAGAH 570
            |..|| |..|..|....|..|          |||| ||           |.|.|:..| |||...
Mouse   344 DPCNS-SLASLRLKAKQHASF----------SYPAVPG-----------PPPAANLSPCQYAVER 386

  Fly   571 P 571
            |
Mouse   387 P 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	24/90 (27%)
		Homeodomain	214..270	CDD:459649	34/55 (62%)
Pitx3	XP_006526827.1	Homeodomain	149..205	CDD:459649	34/55 (62%)
		PTZ00395	<228..>322	CDD:185594	28/155 (18%)
		OAR	344..361	CDD:461067	6/17 (35%)