Protein Alignment prd and Pax6

DIOPT Version :9

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001231127.1
• Gene: Pax6 / 18508
• MGIID: 97490
• Length: 436
• Species: Mus musculus
• Alignment Length: 498
• Identity: 182/498 - (36%)
• Similarity: 242/498 - (48%)
• Gaps: 124/498 - (24%)

  Fly    21 MQDMNSGQGRVNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLR--------------V 71
            ||:.:||   ||||||||:||||||::.|.||||:|..|.|||.|||.|:              |
Mouse     1 MQNSHSG---VNQLGGVFVNGRPLPDSTRQKIVELAHSGARPCDISRILQTHADAKVQVLDNENV 62

  Fly    72 SHGCVSKILNRYQETGSIRPGVIGGSKPRIATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCD 136
            |:|||||||.||.|||||||..|||||||:||||:.::|.:|||..|.:|:||||::|:.||||.
Mouse    63 SNGCVSKILGRYYETGSIRPRAIGGSKPRVATPEVVSKIAQYKRECPSIFAWEIRDRLLSEGVCT 127

  Fly   137 RSTAPSVSAISRLVR---------GRDAPLD-----NDMSSASGSPAG-------DGTKASSSCG 180
            ....||||:|:|::|         |.|...|     |..:.:.|:..|       .|......|.
Mouse   128 NDNIPSVSSINRVLRNLASEKQQMGADGMYDKLRMLNGQTGSWGTRPGWYPGTSVPGQPTQDGCQ 192

  Fly   181 SDVSGGHHNNGKPSDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREE 245
            ....||.:.|...|:.:.|| |::..:.||||.:|.||:|:..|::.||:.||||.|||::.||.
Mouse   193 QQEGGGENTNSISSNGEDSD-EAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDVFARER 256

  Fly   246 LAQRTNLTEARIQVWFSNRRA------RLRKQHTSVSGGAPGGAAASVSHVAASSS--------L 296
            ||.:.:|.|||||||||||||      :||.|....|.        :.||:..|||        :
Mouse   257 LAAKIDLPEARIQVWFSNRRAKWRREEKLRNQRRQASN--------TPSHIPISSSFSTSVYQPI 313

  Fly   297 PSVVSSVPSMAPLAMMPGSLDPATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQ 361
            |...:.|.|....:|: |..|.|...             :.||..||.|..::..:...||...|
Mouse   314 PQPTTPVSSFTSGSML-GRTDTALTN-------------TYSALPPMPSFTMANNLPMQPPVPSQ 364

  Fly   362 FYNPSANTASY--IMPGENGNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAF 424
                   |:||  ::|     |:|:.|          |..|.|.|..|.....|..|
Mouse   365 -------TSSYSCMLP-----TSPSVN----------GRSYDTYTPPHMQTHMNSQP-------- 399

  Fly   425 GQLPPTPNSLSAVVSGAGVTSSSGANSGADPSQSLANASAGSE 467
                          .|...|:|:|..|   |..|:.....|||
Mouse   400 --------------MGTSGTTSTGLIS---PGVSVPVQVPGSE 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	81/149 (54%)
		Homeobox	217..269	CDD:278475	31/57 (54%)
Pax6	NP_001231127.1	PAX	4..142	CDD:128645	80/140 (57%)
		Homeobox	228..281	CDD:395001	31/52 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0849
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810