Protein Alignment prd and Evx1

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_031992.1
• Gene: Evx1 / 14028
• MGIID: 95461
• Length: 416
• Species: Mus musculus
• Alignment Length: 531
• Identity: 114/531 - (21%)
• Similarity: 173/531 - (32%)
• Gaps: 178/531 - (33%)

  Fly    37 VFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPRI 101
            :|::|..|...:..::..::.....|.....:..|.|||:|                     ||.
Mouse     9 MFLDGGQLGTLVGKRVSNLSEAVSSPLPEPPEKMVPHGCLS---------------------PRA 52

  Fly   102 ATP---------EIENRIEEYKRSSPGMFSWEIREKLIREGVCDRST----------APSVSAIS 147
            ..|         :.|..::....|:.|:            |...||.          .||..::|
Mouse    53 GPPTSRERGGGGQEEEPVDGLAGSAAGL------------GAEPRSAGAAMLGPGPPVPSADSLS 105

  Fly   148 RLVRGRDAPLDNDMSS--------------ASG--------SPAGDGTKASSSCGSDVSGGHHNN 190
                |:..|..:|..|              |:|        :|..|...:|.:.||:....:..:
Mouse   106 ----GQGQPSSSDTESDFYEEIEVSCTPDCATGNAEYQHSKAPGSDALGSSPTSGSEAPKSNGGS 166

  Fly   191 GKPSDEDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEA 255
            |....:....|.:..      :.||.||.|:..|:..||:.|.|..|.....|.|||...||.|.
Mouse   167 GGSGSQGTLACSASD------QMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPET 225

  Fly   256 RIQVWFSNRRARLRKQHTSVSGGAPGGAA---ASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLD 317
            .|:|||.|||.:.::|..:::...|...|   ..:||.||:..||   ...||..||.
Mouse   226 TIKVWFQNRRMKDKRQRLAMTWPHPADPAFYTYMMSHAAAAGGLP---YPFPSHLPLP------- 280

  Fly   318 PATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIMPGENGNTT 382
                       |.|...:..::||..|:|..|                             |...
Mouse   281 -----------YYSPVGLGAASAASAAASPFS-----------------------------GPLR 305

  Fly   383 PTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGVTSSS 447
            |.....|.|                |..||.|     :..||...|..|.      ...|:.:|:
Mouse   306 PLDTFRVLS----------------QPYPRPE-----LLCAFRHPPLYPG------PAHGLGASA 343

  Fly   448 GANSGADPSQSLANASAGSEELS--AALKVESVDLIAASQSQLYGGWSSMQALRPNAPLSPEDSL 510
            .|.:.|.|...||..|..:..|:  ||....:.|...||.|            |.::.|:...|:
Mouse   344 AAAAAAGPCSCLACHSGPANGLAPRAAAAAAASDFTCASTS------------RSDSFLTFAPSV 396

  Fly   511 NSTSSTSQALD 521
            .|.:|:..|||
Mouse   397 LSKASSVAALD 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	22/135 (16%)
		Homeodomain	214..270	CDD:459649	25/55 (45%)
Evx1	NP_031992.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..120		22/126 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	138..178		6/39 (15%)
		Homeodomain	184..240	CDD:459649	25/55 (45%)