Protein Alignment prd and Poxn

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: XP_314947.5
• Gene: Poxn / 1275678
• VectorBaseID: AGAMI1_009473
• Length: 636
• Species: Anopheles gambiae
• Alignment Length: 609
• Identity: 161/609 - (26%)
• Similarity: 256/609 - (42%)
• Gaps: 158/609 - (25%)

  Fly     3 VTAFAAAMHRPFFNGYSTMQDM-NSGQGRVNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVIS 66
            ::.|..|:::|     .|:.:| ::||..||||||||:||||||:.:|.:|||:|..|:|||.||
Mosquito    60 ISDFKTAINKP-----PTIVEMPHTGQAGVNQLGGVFVNGRPLPDIVRRRIVELALMGVRPCDIS 119

  Fly    67 RQLRVSHGCVSKILNRYQETGSIRPGVIGGSKPR-IATPEIENRIEEYKRSSPGMFSWEIREKLI 130
            |||.||||||||||.|:.||||||||.|||||.: :|||.:..:|..:|:.:||||:||||::|:
Mosquito   120 RQLLVSHGCVSKILTRFYETGSIRPGSIGGSKTKQVATPTVVKKILRFKQENPGMFAWEIRDQLL 184

  Fly   131 REGVCDRSTAPSVSAISRLVRGRDAPLDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKPSD 195
            .:.:||.:|.||||:::|::|                                :||...:...|:
Mosquito   185 SQRICDPNTIPSVSSVNRILR--------------------------------NGGMWTDDMTSN 217

  Fly   196 EDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQY------PDIYTREELAQRTNLTE 254
            |.:....|....|..:.:........:..|::.:....:.:|      ||     ..::..||
Mosquito   218 EQMLRESSHSSSAYMQSKAMSSHPLYSQTLEQHQALLNQYRYSMAAVSPD-----HASKHPNL-- 275

  Fly   255 ARIQVWFSNRRARLRKQHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPA 319
                           ..|.|..|..||.....|...||.:               .:...||.|.
Mosquito   276 ---------------PHHHSPYGSPPGAPGPMVQRTAAVN---------------IIQHESLPPT 310

  Fly   320 TVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHH-----QFYNPSANTA--------- 370
            ...:|..:.:..|      ..:|:.:..|:.|......|||     |...||.:.:
Mosquito   311 GTTKQPPEMHHQH------TVSPLQTQPLTAGHNPHQHHHHHHQQQQHGKPSPSVSMPDLSSPKG 369

  Fly   371 --SYIMPGENGNTTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAF--GQLPP-- 429
              |...|..:..:||||:..|||.......:        ..:|::...|.|:..|.  ||..|
Mosquito   370 GDSKSEPSSSTRSTPTGSTPVSSAPPNPAQM--------PYLPKHWIWNTSLFYAANRGQHAPGA 426

  Fly   430 TPNSLSAVVSGAGVTSSSGANSGADP--------------------SQSLANASAGSEELSAALK 474
            .|:::|:..:.|...:::.|.:.|.|                    ..||.:.:..|...|:.::
Mosquito   427 DPSTVSSAAAAAAAAAAAAAAAAAFPHGYFTYGNPFGGGAPFPGQIESSLRSDTTASNASSSPVQ 491

  Fly   475 VESV---------DLIAASQSQLYGGWSSMQALRPNAPLSPEDSLN--------STSSTSQALDV 522
            :..|         |.:..|.|:....:|..:.|:  .|.|.:..::        |.||.....|.
Mosquito   492 ITDVNSDDSSDNHDELRTSISKKRNPYSIEELLK--KPESKKQKIDDRVTITCISDSSRKTPTDS 554

  Fly   523 TAHQMFHPYQHTPQYA---SYPAP 543
            .....:|.||.:|..:   |.|:|
Mosquito   555 PLDDKYHHYQCSPSVSPSKSCPSP 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	77/127 (61%)
		Homeodomain	214..270	CDD:459649	6/61 (10%)
Poxn	XP_314947.5	None