Protein Alignment prd and Pax3

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_446162.1
• Gene: Pax3 / 114502
• RGDID: 620431
• Length: 484
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 226/547 - (41%)
• Similarity: 292/547 - (53%)
• Gaps: 119/547 - (21%)

  Fly    27 GQGRVNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETGSIRP 91
            ||||||||||||||||||||:||.||||||..||||||||||||||||||||||.||||||||||
  Rat    34 GQGRVNQLGGVFINGRPLPNHIRHKIVEMAHHGIRPCVISRQLRVSHGCVSKILCRYQETGSIRP 98

  Fly    92 GVIGGSKPR-IATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAPSVSAISRLVR---- 151
            |.||||||: :.||::|.:||||||.:|||||||||:||:::.||||:|.||||:|||::|
  Rat    99 GAIGGSKPKQVTTPDVEKKIEEYKRENPGMFSWEIRDKLLKDAVCDRNTVPSVSSISRILRSKFG 163

  Fly   152 -GRDAPLDNDMSSASGSPAGDGTKASSSCGSDVSGGHHNNGKPSDEDISDCESEPGIALKRKQRR 215
             |.:...|.:...|..|.    .||..|....:|   .....|..::.||.:|||.:.|||||||
  Rat   164 KGEEEEADLERKEAEESE----KKAKHSIDGILS---ERASAPQSDEGSDIDSEPDLPLKRKQRR 221

  Fly   216 CRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVWFSNRRARLRKQHTSVSGGA- 279
            .||||:|.||:|||||||||.|||||||||||||..|||||:||||||||||.|||     .||
  Rat   222 SRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTEARVQVWFSNRRARWRKQ-----AGAN 281

  Fly   280 ---------PGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDP-ATVYQQQYDFYGSHAN 334
                     |||...:     |..:||:...|..|..|.::.....|| :||::.|
  Rat   282 QLMAFNHLIPGGFPPT-----AMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQ--------- 332

  Fly   335 ISVSAAAPMASSNLSPGITTTPPHHHQFYNPS--ANTASYIMPGENGNTTPTGNIIVSSYETQLG 397
                   |:..|.:           ||...||  .::::|.:|...
  Rat   333 -------PLPPSTV-----------HQSTIPSNADSSSAYCLPSTR------------------- 360

  Fly   398 SVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLSAVVSGAGVTSSSGANSGADPSQSLANA 462
              :|..:.|...:|.: .|:..::.|.|      |.||..|.|. :|:..|.........:|:..
  Rat   361 --HGFSSYTDSFVPPS-GPSNPMNPAIG------NGLSPQVMGL-LTNHGGVPHQPQTDYALSPL 415

  Fly   463 SAGSEELSAALKVESVDLIAASQSQLYGGWSSMQALRPNAPLSPEDSLNSTSSTSQALD-VTAHQ 526
            :.|         :|....::||.||......::.:|..:.|..|.    :.|:|..::| ||.:
  Rat   416 TGG---------LEPTTTVSASCSQRLEHMKNVDSLPTSQPYCPP----TYSTTGYSMDPVTGY- 466

  Fly   527 MFHPYQHTPQYASYPAPGHAHSHHGHP 553
                     ||..|   |.:..|:..|
  Rat   467 ---------QYGQY---GQSAFHYLKP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	101/132 (77%)
		Homeodomain	214..270	CDD:459649	46/55 (84%)
Pax3	NP_446162.1	PAX	34..159	CDD:128645	99/124 (80%)
		Homeodomain	220..276	CDD:459649	46/55 (84%)
		Pax7	347..391	CDD:403540	11/71 (15%)