DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment prd and pax10

DIOPT Version :9

Sequence 1:	NP_723721.1	Gene:	prd / 34629	FlyBaseID:	FBgn0003145	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001373372.1	Gene:	pax10 / 100192208	ZFINID:	ZDB-GENE-081022-10	Length:	275	Species:	Danio rerio

Alignment Length:	291	Identity:	84/291 - (28%)
Similarity:	117/291 - (40%)	Gaps:	95/291 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 EDISDCESEPGIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEARIQVW 260
            :::.|  |:..:.||||.:|.||:|:..|:|.||:.||||.|||::.||.||.:.:|.|||||||
Zfish    59 DEVDD--SQLHLQLKRKLQRNRTSFTQEQIDALEKEFERTHYPDVFARERLAAKIDLPEARIQVW 121

  Fly   261 FSNRRA------RLRKQHTSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMAPLAMMPGSLDPA 319
            ||||||      :||.|..|.|     .::.|.:|...|:|..|.|
Zfish   122 FSNRRAKWRREEKLRNQRRSGS-----SSSCSQTHTPLSTSFNSPV------------------- 162

  Fly   320 TVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASY--IMPGENGNTT 382
                     |.||.:.|..:....:.|:|| |.::..........||.:|.:|  ::|.......
Zfish   163 ---------YHSHHSNSSGSMHSRSDSSLS-GYSSLSVFSSMQSLPSQSTPTYSCMLPPSPSALP 217

  Fly   383 PTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSLS-----AVVSGAG 442
            |......|||           |..|                   |||.|.:.:     |.||.||
Zfish   218 PLSRKFDSSY-----------TSPH-------------------LPPPPTASANTGFFAGVSAAG 252

  Fly   443 VTSSSGANSGADPSQSLANASAGSEELSAAL 473
            .|:..|                |.:||...|
Zfish   253 QTAVQG----------------GDQELGQGL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076
prd	NP_723721.1	Homeobox	217..269	CDD:278475	32/57 (56%)
pax10	NP_001373372.1	Homeobox	78..131	CDD:395001	32/52 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000011
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910