Protein Alignment prd and phox2b

DIOPT Version :10

• Sequence 1: NP_723721.1
• Gene: prd / 34629
• FlyBaseID: FBgn0003145
• Length: 613
• Species: Drosophila melanogaster
• Sequence 2: NP_001116492.1
• Gene: phox2b / 100124329
• XenbaseID: XB-GENE-1000415
• Length: 293
• Species: Xenopus tropicalis
• Alignment Length: 329
• Identity: 100/329 - (30%)
• Similarity: 133/329 - (40%)
• Gaps: 86/329 - (26%)

  Fly   144 SAISRLVRGRD----APLDNDMSS---ASG---SPAGDGTKASSSCGSDVSGGHHNNGKPSDEDI 198
            ||....:.|.|    |....|.||   |||   :|......|:|.|.| ::.|..:.|...|...
 Frog    12 SAYESCMAGMDTSSLASAYADFSSCSQASGFQYNPIRTTFGATSGCPS-LTPGSCSLGTLRDHQS 75

  Fly   199 SDCESEP--------GIALKRKQRRCRTTFSASQLDELERAFERTQYPDIYTREELAQRTNLTEA 255
            |...:.|        |:..||||||.||||:::||.||||.|..|.|||||||||||.:.:||||
 Frog    76 SPYAAVPYKLFTDHGGLNEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEA 140

  Fly   256 RIQVWFSNRRARLRKQH---TSVSGGAPGGAAASVSHVAASSSLPSVVSSVPSMA--------PL 309
            |:||||.||||:.|||.   .:.:..|..|::...|..:.........|:.|...        |.
 Frog   141 RVQVWFQNRRAKFRKQERAAAAAAAAAKNGSSGKKSDSSRDEESKDSKSADPDSTGGPGNNPNPT 205

  Fly   310 AMMPGSLDPATVYQQQYDFYGSHANISVSAAAPMASSNLSPGITTTPPHHHQFYNPSANTASYIM 374
            ....|...|:          |:..|     ..|.     .||....|       .|.:.|::.::
 Frog   206 PSCGGGPSPS----------GAQGN-----GVPQ-----EPGKVGVP-------GPGSLTSASVV 243

  Fly   375 PGENGN-----TTPTGNIIVSSYETQLGSVYGTETETHQTMPRNESPNESVSSAFGQLPPTPNSL 434
             |.:|.     |.|.|.|  :|....||                 .|..||.|:..:    |||.
 Frog   244 -GVSGGPQGWATGPGGTI--TSIPDSLG-----------------GPFASVLSSLQR----PNST 284

  Fly   435 SAVV 438
            .|.:
 Frog   285 KATL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
prd	NP_723721.1	PAX	27..154	CDD:238076	3/9 (33%)
		Homeodomain	214..270	CDD:459649	38/55 (69%)
phox2b	NP_001116492.1	Homeodomain	99..155	CDD:459649	38/55 (69%)