Protein Alignment firl and BDH1

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: XP_011511369.1
• Gene: BDH1 / 622
• HGNCID: 1027
• Length: 347
• Species: Homo sapiens
• Alignment Length: 197
• Identity: 51/197 - (25%)
• Similarity: 90/197 - (45%)
• Gaps: 19/197 - (9%)

  Fly    38 FVSLVQIVLPKKQKDVSGEIVLITGTGHGIGRELALHYASLGSTVV--CVDID-GKNNLQTVEKA 99
            |:.:.:.......:.|..:.||:||...|.|..||.|..|.|..|.  |:..| |.:.::.::.
Human    42 FIPIGRRTYASAAEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDS- 105

  Fly   100 KRLNLGEVYSYSCDVSKRDEVTALADRIKSDV--------GCISVLVNNVGIMPTHPILQQSAEE 156
              ||...:.:...:|...:||..:.:.::|.:        |    ||||.||.....:...|.|.
Human   106 --LNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWG----LVNNAGISTFGEVEFTSLET 164

  Fly   157 IQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLMEALHA 221
            .::|.:||::......::||| :..:.:|.::.:||:.|.:......|||.|||.|....:.|..
Human   165 YKQVAEVNLWGTVRMTKSFLP-LIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRY 228

  Fly   222 EL 223
            |:
Human   229 EM 230

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	49/178 (28%)
BDH1	XP_011511369.1	type2_17beta_HSD-like_SDR_c	60..345	CDD:187665	49/179 (27%)