Protein Alignment firl and hsd17b12

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001017234.1
• Gene: hsd17b12 / 549988
• XenbaseID: XB-GENE-945229
• Length: 320
• Species: Xenopus tropicalis
• Alignment Length: 201
• Identity: 55/201 - (27%)
• Similarity: 87/201 - (43%)
• Gaps: 15/201 - (7%)

  Fly    55 GEIVLITGTGHGIGRELALHYASLGSTVVCVDIDGKNNLQTVEKAKRLNLGEVYSYSCDVSKRDE 119
            |:..::||...|||:..|...|..|..:|.:....:...:..::.|.....|....:.|..|..|
 Frog    56 GKWAVVTGATDGIGKAYAEELAKRGMNIVLISRSPEKLEEVAKQIKEKFKVETKIIAADFGKPTE 120

  Fly   120 VTALADRIKSDVGC--ISVLVNNVGIMPTHPILQQSAEEIQRVFD----VNVFSQFWTIQAFLPH 178
            :..   ||:|.:..  |.|||||||:...||.......:::...|    :|:.|.....:..||.
 Frog   121 IYG---RIESGLRDLEIGVLVNNVGVSYEHPEYFLEIPDLENTLDKMININITSVCQMTRLVLPG 182

  Fly   179 MQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLMEALHAELR-QGPFRDLIRTTTIFPYMT 242
            |..:.||.|:.:||.:|:..:..|..|.|||..|......|.||.| :|     :...::.|:..
 Frog   183 MLGRGRGVILNISSASGMYPVPLLTVYSATKAFVDFFSRGLQAEYRSKG-----VTVQSVLPFYV 242

  Fly   243 NTGLCK 248
            .|.|.|
 Frog   243 ATKLAK 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	54/199 (27%)
hsd17b12	NP_001017234.1	17beta-HSD1_like_SDR_c	56..297	CDD:187614	55/201 (27%)