Protein Alignment firl and hsd17b11

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001011304.1
• Gene: hsd17b11 / 496757
• XenbaseID: XB-GENE-1004190
• Length: 300
• Species: Xenopus tropicalis
• Alignment Length: 290
• Identity: 100/290 - (34%)
• Similarity: 168/290 - (57%)
• Gaps: 13/290 - (4%)

  Fly    23 VLQFFELYVRILLELFVSLVQIVLPKKQKDVSGEIVLITGTGHGIGRELALHYASLGSTVVCVDI 87
            :|:...|.:.|:.....|.|::.:|.|:|.|.||:|||||.|||||:..|..:..|.|.:|..||
 Frog     4 LLEIVWLLLVIVYSYLESFVKLFIPLKRKSVKGEVVLITGAGHGIGKITAQIFGELESVLVLWDI 68

  Fly    88 DGKNNLQTVEKAKRLNLGEVYSYSCDVSKRDEVTALADRIKSDVGCISVLVNNVGIMPTHPILQQ 152
            :.:...:|.||.:: ...:||:|..|.|||:|:...|:::|.:||.:::|:||.||:....:|..
 Frog    69 NKQGVEETAEKCRK-GGAKVYTYVVDCSKREEINTAANKVKQEVGDVTILINNAGIIFCADVLTL 132

  Fly   153 SAEEIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLME 217
            ..::|:::|:||:.:.|||.:||||.|.....|||:.::|.||.||:..:|.||:||||..|..:
 Frog   133 QDQQIEKIFEVNILAHFWTTRAFLPSMLRNNHGHIVTVASSAGFVGVQFMVDYCSTKFAALGYHK 197

  Fly   218 ALHAEL----RQGPFRDLIRTTTIFPYMTNTGLCKHPKVKFPSILGLLDPKQVAKRIVEAHRTDL 278
            ||.|||    :.|     |:|:.:.|...:||..|:|.::...:   |.|::||:.:|:....:.
 Frog   198 ALTAELLALGKSG-----IKTSCLCPVFVDTGFVKNPSLRLAPV---LQPEEVAQTLVDGILINK 254

  Fly   279 MEVTIPSCLLYINNWTRLLPDHCGLMLKDF 308
            ..:.:||.:..:......||:.....|.:|
 Frog   255 KMICVPSSVSLVPVLAFFLPERALNALNEF 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	86/245 (35%)
hsd17b11	NP_001011304.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	87/247 (35%)