Protein Alignment firl and sdr16c5

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001004963.1
• Gene: sdr16c5 / 448386
• XenbaseID: XB-GENE-942748
• Length: 305
• Species: Xenopus tropicalis
• Alignment Length: 290
• Identity: 104/290 - (35%)
• Similarity: 170/290 - (58%)
• Gaps: 12/290 - (4%)

  Fly    26 FFELYVRILLELFVSLVQIVL---PKKQKDVSGEIVLITGTGHGIGRELALHYASLGSTVVCVDI 87
            |.|....:.|.::::|...||   |.::|:|:||||||||.|.||||.:||.:|.||:|:|..||
 Frog     4 FLETLKVLFLTIYLNLESFVLWFIPSRKKNVAGEIVLITGAGSGIGRLMALEFAHLGATLVLWDI 68

  Fly    88 DGKNNLQTVEKAKRLNLGEVYSYSCDVSKRDEVTALADRIKSDVGCISVLVNNVGIMPTHPILQQ 152
            :.:.|.:|...||:.....|::|.||.|||.||..:||::|.:||.:|:|:||.||:.....:..
 Frog    69 NEEGNKETCRLAKKNGAVRVHAYLCDCSKRQEVYKVADQVKKEVGDVSILINNAGIVTGKKFIDS 133

  Fly   153 SAEEIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLME 217
            ....:::...||..:.|||.:||||.|.....||::.::|.|||:|::.|..|||:|||..|..|
 Frog   134 PDALVEKTMQVNCMAHFWTYKAFLPAMMASNHGHLVSIASSAGLIGVNGLADYCASKFAAVGFAE 198

  Fly   218 ALHAEL----RQGPFRDLIRTTTIFPYMTNTGLCKHPKVKFPSILGLLDPKQVAKRIVEAHRTDL 278
            ::..|:    :.|     |:||.:.||..|||:......|:|.:|.:|:.:..:|:||:|...|.
 Frog   199 SVGLEMLALGKTG-----IKTTIVCPYFINTGMFDGCSTKWPRLLPILEAEYASKKIVDAILKDQ 258

  Fly   279 MEVTIPSCLLYINNWTRLLPDHCGLMLKDF 308
            :.:.:|..|..:.....::....|::|.::
 Frog   259 VYLVMPRSLYIMFALKNIMSTKLGVVLGNY 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	91/245 (37%)
sdr16c5	NP_001004963.1	17beta-HSDXI-like_SDR_c	38..281	CDD:187598	91/247 (37%)