Protein Alignment firl and hsd20b2

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001373557.1
• Gene: hsd20b2 / 368367
• ZFINID: ZDB-GENE-030804-21
• Length: 329
• Species: Danio rerio
• Alignment Length: 222
• Identity: 59/222 - (26%)
• Similarity: 92/222 - (41%)
• Gaps: 42/222 - (18%)

  Fly    55 GEIVLITGTGHGIGRELALHYASLGSTVVCV------------DIDGKNNLQT-VEKAKRLNLGE 106
            |...::||...||||..|...|..|..:|.:            :|:.|.|.:| |.:|.......
Zfish    54 GRWAVVTGATSGIGRAYAEELAKRGLNIVLISRSEEKLHRVAKEIEDKYNQKTHVIQADFTEGHS 118

  Fly   107 VYSYSCDVSKRDEVTALADRIKSDVGCISVLVNNV-----GIMPTHPILQQSAEEIQRVFDVNVF 166
            :||         .:|...:.::     |.:|||||     |::.....:....:.|.:|.:.|..
Zfish   119 IYS---------TITKQLEGLE-----IGILVNNVGMNYIGVLANFLDVPDPDQRITQVLNCNTL 169

  Fly   167 SQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLMEALHAELR-QGPFRD 230
            |.....:..||.|.|:.:|.||.:||.||...:..:..|.|||..|......|:||.| :|
Zfish   170 SVTQMCRVILPGMVERGKGLIINISSEAGYQPVPMVSLYSATKAFVTYFSLGLNAEYRSKG---- 230

  Fly   231 LIRTTTIFPYMTNTGLCK----HPKVK 253
             |....:.|:|.:|.:..    :|.||
Zfish   231 -ITVQCVAPFMVSTNMTHNVPVNPLVK 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	58/220 (26%)
hsd20b2	NP_001373557.1	17beta-HSD1_like_SDR_c	54..296	CDD:187614	59/222 (27%)