Protein Alignment firl and CG6012

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_609817.1
• Gene: CG6012 / 35022
• FlyBaseID: FBgn0032615
• Length: 308
• Species: Drosophila melanogaster
• Alignment Length: 255
• Identity: 67/255 - (26%)
• Similarity: 108/255 - (42%)
• Gaps: 38/255 - (14%)

  Fly    51 KDVSGEIVLITGTGHGIGRELALHYASLGSTVVCVDIDGKNNLQTVEKAKRLNLG---EVYSYSC 112
            |:..|:...:||...|||:|.|...|.....||.: ...:..||.|.| :..:.|   :......
  Fly    45 KERFGDWAAVTGASDGIGKEYAKELARQNINVVLI-ARTEEKLQAVAK-EIADCGAGVQTKIVIA 107

  Fly   113 DVSKRDEVTALADRIKSDVGCISVLVNNVGIMPTHPILQQSAEEIQRVFDVNVFSQFWTIQAFLP 177
            |.:|..:|....::..:::. ||:|||||||.....:|:.:.||.|.:.|.||.:.....:.|..
  Fly   108 DFTKGSQVYEHIEKETANIP-ISILVNNVGIATPKSLLKYNQEETQNIIDTNVVAVSQLSRIFFQ 171

  Fly   178 HMQ-EKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLMEALHAELRQGPFRDLIRTTTIFPYM 241
            .|: .|.:|.|:.:.|...|..:.|...|.|:|...|.|..||:.|.:              ||
  Fly   172 RMKASKLKGAIVNVGSGTELQPLPNGAYYAASKAYTRSLTLALYHEAK--------------PY- 221

  Fly   242 TNTGLCKHPKVKFPSILGLLDPKQVAKRIVEAHRTDLME--VTIPSCLLYINNWTRLLPD 299
               |:  |        :.:|.|..|..:| .::...:|:  :.|||...|..:....|.|
  Fly   222 ---GI--H--------VQMLSPNFVVTKI-NSYSRQIMKGGLLIPSASAYAKSAVNQLRD 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	64/247 (26%)
CG6012	NP_609817.1	17beta-HSD1_like_SDR_c	49..296	CDD:187614	66/251 (26%)