Protein Alignment firl and Hsd17b11

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001004209.1
• Gene: Hsd17b11 / 289456
• RGDID: 1303235
• Length: 298
• Species: Rattus norvegicus
• Alignment Length: 297
• Identity: 99/297 - (33%)
• Similarity: 165/297 - (55%)
• Gaps: 27/297 - (9%)

  Fly    20 LKDVLQFFELYVRILLELFVSLVQIVLPKKQKDVSGEIVLITGTGHGIGRELALHYASLGSTVVC 84
            |.|::....|.:...:|   |.::.::|||:|.|:||||||||.||||||..|..:|.|.:.:|.
  Rat     4 LLDLILLLPLLIVFCIE---SFIKRLIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVL 65

  Fly    85 VDIDGKNNL-QTVEKAKRLNLGEVYSYSCDVSKRDEVTALADRIKSDVGCISVLVNNVGIMPTHP 148
            .||: ||.: :|..|.::|. .:|:.:..|.|:|:|:.:...::|.:||.:|:||||.|::.|..
  Rat    66 WDIN-KNGIEETAAKCRKLG-AQVHPFVVDCSQREEIYSAVRKVKEEVGDVSILVNNAGVVYTAD 128

  Fly   149 ILQQSAEEIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVR 213
            :......:|::.|:|||.:.|||.:||||.|.:...||::.::|.||...:..|:.||::|||..
  Rat   129 LFATQDPQIEKTFEVNVLAHFWTTKAFLPAMMKNNHGHVVTVASAAGHTVVPFLLAYCSSKFAAV 193

  Fly   214 GLMEALHAELR----QGPFRDLIRTTTIFPYMTNTGLCKHPKVKFPSILG-LLDPKQVAKRIVEA 273
            |...||..||.    .|     :||:.:.|...|||..|:|...    || .|:|::|.:.::..
  Rat   194 GFHRALTDELAALGCTG-----VRTSCLCPNFINTGFIKNPSTN----LGPTLEPEEVVEHLMHG 249

  Fly   274 HRTDLMEVTIPSCLLYINNWTRLLPDHCGLMLKDFID 310
            ..|:...:.:|..:..:....|:.|:.       |:|
  Rat   250 ILTNQKMIFVPGSIALLTVLERVFPER-------FLD 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	84/247 (34%)
Hsd17b11	NP_001004209.1	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	85/256 (33%)