Protein Alignment firl and SDR16C5

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001304978.1
• Gene: SDR16C5 / 195814
• HGNCID: 30311
• Length: 318
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 107/289 - (37%)
• Similarity: 170/289 - (58%)
• Gaps: 19/289 - (6%)

  Fly    12 ASKRIFDVLKDVLQFFELYVRILLELFVSLVQIVLPKKQKDVSGEIVLITGTGHGIGRELALHYA 76
            :||::|..|.          :.|..|..:::..:|||.:|:|:||||||||.|.|:||.|||.:|
Human     7 SSKKLFIFLG----------KSLFSLLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFA 61

  Fly    77 SLGSTVVCVDIDGKNNLQTVEKAKRLNLGEVYSYSCDVSKRDEVTALADRIKSDVGCISVLVNNV 141
            .|||.:|..||:.:.|.:|.:.|:......|::|:||.|:::.|..:||::|.:||.:|:|:||.
Human    62 RLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNA 126

  Fly   142 GIMPTHPILQQSAEEIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYC 206
            ||:.....|....|.:::.||||..:..||.:||||.|.....||::|:||.|||.|::.|..||
Human   127 GIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYC 191

  Fly   207 ATKFAVRGLMEALHAEL----RQGPFRDLIRTTTIFPYMTNTGLCKHPKVKFPSILGLLDPKQVA 267
            |:|||..|..|::..|.    ::|     |:||.:.|:...||:.:......||:|.:|:||...
Human   192 ASKFAAFGFAESVFVETFVQKQKG-----IKTTIVCPFFIKTGMFEGCTTGCPSLLPILEPKYAV 251

  Fly   268 KRIVEAHRTDLMEVTIPSCLLYINNWTRL 296
            ::||||...:.|.:.:|..|.::....||
Human   252 EKIVEAILQEKMYLYMPKLLYFMMFLKRL 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	94/244 (39%)
SDR16C5	NP_001304978.1	17beta-HSDXI-like_SDR_c	42..280	CDD:187598	92/242 (38%)