Protein Alignment firl and F02C12.2

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_510229.1
• Gene: F02C12.2 / 184076
• WormBaseID: WBGene00008516
• Length: 278
• Species: Caenorhabditis elegans
• Alignment Length: 212
• Identity: 60/212 - (28%)
• Similarity: 96/212 - (45%)
• Gaps: 25/212 - (11%)

  Fly    46 LPKKQKDVSGEIVLITGTGHGIGRELALHYASLGSTVVCVDIDGKNNLQTVEKAKRLNLGEVYSY 110
            :||:   .|.::.:|||:..|||||.||.:|..|:.|.   :.|::. :.:|:.|:..|......
 Worm     1 MPKR---FSKKVAIITGSSSGIGRETALLFAKEGAKVT---VTGRSE-EKLEETKKALLDAGIKE 58

  Fly   111 S------CDVSKRDEVTALADRIKSDVGCISVLVNNVGI-MP---THPILQQSAEEIQRVFDVNV 165
            |      .|::.......|..:.....|.|::||||.|. :|   ....:.|..|..::|..:||
 Worm    59 SNFLIVPADITFSTGQDELISQTLKKFGRINILVNNAGASIPDAKKRTGIDQGIETYEQVMKLNV 123

  Fly   166 FSQFWTIQAFLPHMQEKCRGHIICMSSIAGL-VGISNLVPYCATKFAV-RGLMEALHAELRQGPF 228
            .|.....|...||: .|.||.|:.:||:..| .|.:....|...|.|: :....|..|.:.:|
 Worm   124 QSVIEMTQKVRPHL-AKSRGEIVNVSSVVALKAGWTRTPYYPLAKAALDQYTRSAAIALISEG-- 185

  Fly   229 RDLIRTTTIFPYMTNTG 245
               ||..|:.|.:..||
 Worm   186 ---IRVNTVNPGIVQTG 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	57/201 (28%)
F02C12.2	NP_510229.1	Rossmann-fold NAD(P)(+)-binding proteins	5..267	CDD:473865	58/205 (28%)