Protein Alignment firl and dhs-29

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_509294.1
• Gene: dhs-29 / 181027
• WormBaseID: WBGene00000992
• Length: 427
• Species: Caenorhabditis elegans
• Alignment Length: 312
• Identity: 95/312 - (30%)
• Similarity: 161/312 - (51%)
• Gaps: 46/312 - (14%)

  Fly    29 LYVRILLEL--FVSLVQIVLPKKQKDVSGEIVLITGTGHGIGRELALHYASLGSTVVCVDIDGKN 91
            |::.|.:::  |::|       :||.|.|:.|:|||.|.|:||.:||.:|...:.|..:|::.:.
 Worm    20 LFIDIPMDIHRFLNL-------RQKSVQGQTVIITGGGSGLGRAMALDFAKRKAKVAIIDVNKEG 77

  Fly    92 NLQTVEK-AKRLNLGEVYSYSCDVSKRDEVTALADRIKSDVGCISVLVNNVGIMPTHPILQQSAE 155
            .|:||:. |...|:.:.  :.||:|..|.:...|..|:...|.:::::.|..|:.....::.|.|
 Worm    78 GLETVKTIAAEGNMAKF--WYCDISDVDNMKKTAKEIEDTFGDVNIVICNAAILSFTSFMEISDE 140

  Fly   156 EIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLMEALH 220
            .:::..|||:|....||:||||.|:.|..|||:|:.||||..|.:..:.||.:||||||.||:|.
 Worm   141 LLRKCLDVNIFGTINTIRAFLPKMETKNDGHIVCVCSIAGWSGETMGLSYCTSKFAVRGAMESLQ 205

  Fly   221 AELRQGPFRDL--IRTTTIFPYMTNTGLCKHPKVK-----FPSILGLLDPKQVAKRIVEAHRTDL 278
            .|||.   |.|  |:|||::||...|.:.....::     ||    .:..:..:||:|::...:.
 Worm   206 MELRD---RGLEGIKTTTLYPYFARTPMILENNMRPTCTWFP----FMSIRSCSKRMVDSILKEK 263

  Fly   279 MEVTIPSCLL---YINNWTRLL-----------------PDHCGLMLKDFID 310
            :...:||.:.   ::.|:..|.                 |..|.|.|.:..|
 Worm   264 VHAFVPSYITLIPFVKNFCSLQVCRSLRNYLGVKYSASDPSFCKLTLIEMSD 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	82/269 (30%)
dhs-29	NP_509294.1	Rossmann-fold NAD(P)(+)-binding proteins	43..281	CDD:473865	80/246 (33%)
		TMEM254	<372..416	CDD:464385