Protein Alignment firl and dhs-19

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_505915.1
• Gene: dhs-19 / 179578
• WormBaseID: WBGene00000982
• Length: 307
• Species: Caenorhabditis elegans
• Alignment Length: 298
• Identity: 96/298 - (32%)
• Similarity: 154/298 - (51%)
• Gaps: 14/298 - (4%)

  Fly    15 RIFDVLKDVL--QFFELYVRILLELFVS-LVQIVLPKKQKDVSGEIVLITGTGHGIGRELALHYA 76
            |..|.:|.|:  .||     |:|..|.: |...|||:  |.|.|:.|||||:|.||||.:||.:|
 Worm     3 RALDFVKMVVGTLFF-----IVLNFFKNFLPNGVLPR--KSVEGKKVLITGSGSGIGRLMALEFA 60

  Fly    77 SLGSTVVCVDIDGKNNLQTVEKAKRLNLGEVYSYSCDVSKRDEVTALADRIKSDVGCISVLVNNV 141
            .||:.||..|::.....:|..:..:.. |:..::..|:|:..::..:|...|..||.|.:|:||.
 Worm    61 KLGAEVVIWDVNKDGAEETKNQVVKAG-GKASTFVVDLSQYKDIHKVAKETKEAVGDIDILINNA 124

  Fly   142 GIMPTHPILQQSAEEIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYC 206
            ||:....:.....|.:::...||..:.|:|.:.|||.|.||..||::.::|:||..|...||.||
 Worm   125 GIVTGKKLFDCPDELMEKTMAVNTNALFYTAKNFLPSMLEKDNGHLVTIASMAGKTGCVGLVDYC 189

  Fly   207 ATKFAVRGLMEALHAE-LRQGPFRDLIRTTTIFPYMTNTGLCKHPKVKFPSILGLLDPKQVAKRI 270
            |:|....|..:::..| |.|..:.  :.||.:.|:..:||:......|.|::..:|:.....:.|
 Worm   190 ASKHGAIGCHDSIAMEILAQKKYG--VNTTLVCPFFIDTGMFHGVTTKCPALFPILEANYAVECI 252

  Fly   271 VEAHRTDLMEVTIPSCLLYINNWTRLLPDHCGLMLKDF 308
            |||..|:...:.:|.....|.....|||....:|:.||
 Worm   253 VEAILTNRPLLCMPKASYLILALIGLLPIESQVMMADF 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	76/242 (31%)
dhs-19	NP_505915.1	17beta-HSDXI-like_SDR_c	42..282	CDD:187598	77/242 (32%)