Protein Alignment firl and dhs-4

DIOPT Version :10

• Sequence 1: NP_001033900.2
• Gene: firl / 34627
• FlyBaseID: FBgn0032405
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_492563.1
• Gene: dhs-4 / 172810
• WormBaseID: WBGene00000968
• Length: 305
• Species: Caenorhabditis elegans
• Alignment Length: 301
• Identity: 100/301 - (33%)
• Similarity: 166/301 - (55%)
• Gaps: 16/301 - (5%)

  Fly    16 IFDVLKDVLQFFELYVRILLELFVSLVQIVLPKK---QKDVSGEIVLITGTGHGIGRELALHYAS 77
            :||:   :|:...|...:|::..:||::..||..   :||:..:.|||||.|:|:|:.||..:|:
 Worm     1 MFDI---ILEIVILLFNLLIQNLISLIKYALPYSLLPKKDLYRKKVLITGAGNGLGKLLAQKFAA 62

  Fly    78 LGSTVVCVDIDGKNNLQTVEKAK---RLNLGEVYSYSCDVSKRDEVTALADRIKSDVGCISVLVN 139
            .|:|::..||    |||:|::.|   |.|.||.:||..::....::..:..::.:|:|.:.:|||
 Worm    63 RGATLILWDI----NLQSVDELKNEIRGNQGEAHSYEVNLCDPGKIAQVGQQVINDIGKVDILVN 123

  Fly   140 NVGIMPTHPILQQSAEEIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVP 204
            |.||.....||..|..||.|.|||||.:.|:|:|.|||.|.:...|||:.::|.||.:|.|.|..
 Worm   124 NAGIATAKMILDSSENEINRSFDVNVKAHFYTVQQFLPAMLKDNNGHIVTIASAAGKMGSSGLAD 188

  Fly   205 YCATKFAVRGLMEALHAELRQGPFRDLIRTTTIFPYMTNTGL--CKHPKVKFPSILGLLDPKQVA 267
            |.:||.|..|..::|.||:.:.. ::.::||.:.||..:|.:  ......:||.|..:||...|.
 Worm   189 YSSTKHAAVGFHDSLVAEIMESE-KNGVKTTLVCPYYVHTSMFDATGAATRFPWIFPILDTDYVV 252

  Fly   268 KRIVEAHRTDLMEVTIPSCLLYINNWTRLLPDHCGLMLKDF 308
            ::|.||..|:...:..|.....:....::||.....|:..|
 Worm   253 QKIFEAIETEQEFLVTPRAFYLVFAGIQILPYKAQAMVAQF 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
firl	NP_001033900.2	17beta-HSDXI-like_SDR_c	57..299	CDD:187598	86/246 (35%)
dhs-4	NP_492563.1	17beta-HSDXI-like_SDR_c	43..286	CDD:187598	87/247 (35%)