DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab3-GAP and AT3G14910

DIOPT Version :9

Sequence 1:	NP_609544.2	Gene:	Rab3-GAP / 34626	FlyBaseID:	FBgn0027505	Length:	1341	Species:	Drosophila melanogaster
Sequence 2:	NP_188109.1	Gene:	AT3G14910 / 820720	AraportID:	AT3G14910	Length:	455	Species:	Arabidopsis thaliana

Alignment Length:	505	Identity:	111/505 - (21%)
Similarity:	205/505 - (40%)	Gaps:	119/505 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CGEIRDFKKVQEYFGLGHDDNWLNAI-NHAISPTGELIAMAQGEKLAFLSTCWSSHGNGNTYVLG 71
            |.|:.:....:|.: |.::.|.|:|: :|:::.....:.:                      ::.
plant    15 CEELTELGAGKEGW-LVNNPNLLSALDSHSLALANRFLIL----------------------IVN 56

  Fly    72 WCGELEDPN-QIVTSLTCLPMTQNKSTDGAIEW------TCVAVGLCSGMVTFYTDSGVKLFSQC 129
            | |:.:.|. :|...|:  |:.....|  ||||      ..|..|...|.:..|:.:|..:..|.
plant    57 W-GDPDAPRVKIRPDLS--PIEAESIT--AIEWLVFDDVRVVVAGTSCGYLLVYSVTGDLIHKQI 116

  Fly   130 CQEDPVIGVKLQSAPR---HSEADSLLYIIYPRCLCFIQGQDILPTLNNCRHNVQRGALERSSYP 191
            ..:..::.::::...:   ...:...:.|:.|..:....|       :|.:..||:...|::|
plant   117 VHQSRILKIRVRGTKKDLMQETSSEEICIVLPGVIARFDG-------SNIQSMVQKWVQEKNS-- 172

  Fly   192 TADVVPFQKYKFKQEREAVINDAAISTTQRPPTYDYIVQQTIGLGYFAKVHATPPRSSQVLAAGA 256
                    .:..::.|:....|.. |..||.|...:.|.:. |:...|.|....|
plant   173 --------NFWDQKNRKGDAEDTG-SLYQRLPYQIWNVNKN-GVCVDATVTGVMP---------- 217

  Fly   257 EPYLGFFQAEEGYKTMSLGEVAKDVIGIAY-------KNLLGGIFRRAPEPLP------------ 302
            .|.|....::..|..:::||   |.:..||       ::|:|.|..:.   :|
plant   218 PPLLELQSSQRYYCAVTIGE---DSVISAYRLSEDRGRSLVGAILSKV---VPAAASTIASFSKL 276

  Fly   303 ---SPEESPLPVPTKEAPMRIRCR----LYDGKRDGLTLSVAPGGRLAVVTDNLDRVMLVDTHQA 360
               |.::||...|..:.....|..    :.|..|.|..|:::|.|.||.:||:|.|::|:||...
plant   277 IWRSNDQSPKRKPEAKTQSFARASSLTCIKDYPRKGEKLTLSPSGTLAAITDSLGRILLLDTQAL 341

  Fly   361 IILRVWKGYRDAQCAFVPVKEKSVRG---IKTHKRKA---LFLVIYAPRMGCLDIWALQNGPKVA 419
            :::|:|||||||.|.|:.:..|..:|   |.|...|:   |.|.|:|||.|.:::|.::.||::.
plant   342 VVVRLWKGYRDASCVFMEMLAKKDKGKSVIHTEPVKSDYCLCLAIHAPRKGIIEVWQMRTGPRLL 406

  Fly   420 AFNVSKSGQLMYNNHSPLGSGGSS------------GSGNSSSQSRKSLA 457
            ....:|..:|:...:. .||..||            |.....|...:||:
plant   407 TIQCAKGSKLLQPAYR-FGSNSSSSPYIPLEVFLLNGDSGQVSMLNRSLS 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab3-GAP	NP_609544.2	RAB3GAP2_N	29..430	CDD:291327	97/443 (22%)
Rab3-GAP	NP_609544.2	RAB3GAP2_C	710..1319	CDD:291328
AT3G14910	NP_188109.1	RAB3GAP2_N	28..417	CDD:405358	99/451 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	90	1.000	Domainoid score	I2679
eggNOG	1	0.900	-	-		E1_KOG2727
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H40842
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D790713at2759
OrthoFinder	1	1.000	-	-		FOG0005758
OrthoInspector	1	1.000	-	-		oto3034
orthoMCL	1	0.900	-	-		OOG6_105335
Panther	1	1.100	-	-	LDO	PTHR12472
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4151
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.820