DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment JhI-21 and LYP1

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_014131.1	Gene:	LYP1 / 855453	SGDID:	S000005212	Length:	611	Species:	Saccharomyces cerevisiae

Alignment Length:	560	Identity:	120/560 - (21%)
Similarity:	212/560 - (37%)	Gaps:	151/560 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 EEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWLTCGILSTIGALCYAE 96
            |:|.| ||.|...:...|.:|..||:|:|:..:........|||               .:.|..
Yeast   102 EDKHV-KRALKQRHIGMIALGGTIGTGLFVGISTPLSNAGPVGS---------------LIAYIF 150

  Fly    97 LGTC---ITRSGGDYA---------------YLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSF 143
            :||.   :|:|.|:.|               :|..:||...|:: .|....|......:::....
Yeast   151 MGTIVYFVTQSLGEMATFIPVTSSITVFSKRFLSPAFGVSNGYM-YWFNWAITYAVEVSVIGQVI 214

  Fly   144 AHYAVKPFFPECDPPQNAVKLLA--AICLTLLTTINCLSVKV---------SMKVQDVFTVGKLL 197
            .::..|            |.|.|  ||...::|.:|...|||         |:||..:  :|.|:
Yeast   215 EYWTDK------------VPLAAWIAIFWVIITLMNFFPVKVYGEFEFWVASVKVLAI--MGYLI 265

  Fly   198 ALIMIILSGLYYMATGELENFRNP--W-EGIYTA-----RNIGY--AFYSGLFAFGGWNYLNFVT 252
            ..::|:..|.:....| ...:|||  | .||.::     |.:|:  :..:..|.:.|...:....
Yeast   266 YALIIVCGGSHQGPIG-FRYWRNPGAWGPGIISSDKSEGRFLGWVSSLINAAFTYQGTELVGITA 329

  Fly   253 EELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAVV---NKPEMLSSLAVAVT--FGNRVFGPLA 312
            .|..:|.|.:||||...:..:...|:: :|.:..::   |...:.:|.||..:  |...:.....
Yeast   330 GEAANPRKTVPRAINKVVFRIVLFYIM-SLFFIGLLVPYNDSRLSASSAVIASSPFVISIQNAGT 393

  Fly   313 FMVP-IF---VALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSL 373
            :.:| ||   |.::.....|..::..:|:..:.|:.|:.||.|. :..:|..|...::.|..:.|
Yeast   394 YALPDIFNAVVLITVVSAANSNVYVGSRVLYSLARTGNAPKQFG-YVTRQGVPYLGVVCTAALGL 457

  Fly   374 LMLLTDNVYQLINYFSSVLWLSVVASIAGM-LW-------------LRHK---RPDLPRPIKV-- 419
            |..|..|    .|..::..||..::::||: .|             |:|:   |.|||...|:
Yeast   458 LAFLVVN----NNANTAFNWLINISTLAGLCAWLFISLAHIRFMQALKHRGISRDDLPFKAKLMP 518

  Fly   420 ----HLALPIT------------------FMVSCVTLVLLPNLEEPQNLLIGIGITLAGIPFYYA 462
                :.|..:|                  |..|.::|:||             .:...|...||
Yeast   519 YGAYYAAFFVTVIIFIQGFQAFCPFKVSEFFTSYISLILL-------------AVVFIGCQIYY- 569

  Fly   463 FIARKKKPKC--YGRLSNSVVEICRAIFNTTIIESNEAIN 500
                    ||  ..:|.:..::..|......|.|.:|..|
Yeast   570 --------KCRFIWKLEDIDIDSDRREIEAIIWEDDEPKN 601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	117/552 (21%)
LYP1	NP_014131.1	2A0310	107..583	CDD:273334	112/534 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1752
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.870