Protein Alignment JhI-21 and SLC7A2

DIOPT Version :10

• Sequence 1: NP_609542.1
• Gene: JhI-21 / 34624
• FlyBaseID: FBgn0028425
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: NP_001158243.1
• Gene: SLC7A2 / 6542
• HGNCID: 11060
• Length: 698
• Species: Homo sapiens
• Alignment Length: 444
• Identity: 111/444 - (25%)
• Similarity: 193/444 - (43%)
• Gaps: 95/444 - (21%)

  Fly    30 DGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWLTCGILSTIGALCY 94
            |..|...|.|.|:.::.:|:.||:.:|:|:::. .|.....:|..|.::.:|...:.|.:..|||
Human    63 DSLEDTKLCRCLSTMDLIALGVGSTLGAGVYVL-AGEVAKADSGPSIVVSFLIAALASVMAGLCY 126

  Fly    95 AELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALL--IIRPTT---------------------Q 136
            ||.|..:.::|..|.|..|:.|.|..|:..|..:|  :|..::                     :
Human   127 AEFGARVPKTGSAYLYTYVTVGELWAFITGWNLILSYVIGTSSVARAWSGTFDELLSKQIGQFLR 191

  Fly   137 TIVALSFAHYAVKP-FFPECDPPQNAVKLLAAICLTLLTT-INCLSVKVSMKVQDVFTVGKLLAL 199
            |...:::...|..| ||              |:||.||.. :....||.|..|..|||...:|.|
Human   192 TYFRMNYTGLAEYPDFF--------------AVCLILLLAGLLSFGVKESAWVNKVFTAVNILVL 242

  Fly   200 IMIILSGLYYMATGELENFRNPWE------------------GIYTARN-IGYAFYSGL------ 239
            :.::::|   ...|.:.|::...|                  .||.|.. :.|.|...|
Human   243 LFVMVAG---FVKGNVANWKISEEFLKNISASAREPPSENGTSIYGAGGFMPYGFTGTLAGAATC 304

  Fly   240 -FAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAV-----VNKPEML---- 294
             :||.|::.:....||:::|.|.:|      :.:|||:.|.. :|||.|     :..|..|
Human   305 FYAFVGFDCIATTGEEVRNPQKAIP------IGIVTSLLVCF-MAYFGVSAALTLMMPYYLLDEK 362

  Fly   295 SSLAVAVTFGNRVFGPLAFMVPI--FVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVK 357
            |.|.||..:..  :||..::|..  ..||||  .:.|.:|...|:....|::|.|.|.....:.|
Human   363 SPLPVAFEYVG--WGPAKYVVAAGSLCALST--SLLGSIFPMPRVIYAMAEDGLLFKCLAQINSK 423

  Fly   358 QQTPIPSLIFTCLMSLLMLLTDNVYQLINYFS--SVLWLSVVASIAGMLWLRHK 409
            .:|||.:.:.:..::.||....::..|::..|  :::..|:||  |.:|.||::
Human   424 TKTPIIATLSSGAVAALMAFLFDLKALVDMMSIGTLMAYSLVA--ACVLILRYQ 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_609542.1	2A0308	27..494	CDD:273332	111/444 (25%)
SLC7A2	NP_001158243.1	2A0303	45..648	CDD:273330	111/444 (25%)