DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JhI-21 and slc7a7

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001032648.1	Gene:	slc7a7 / 641560	ZFINID:	ZDB-GENE-051127-5	Length:	501	Species:	Danio rerio

Alignment Length:	450	Identity:	214/450 - (47%)
Similarity:	309/450 - (68%)	Gaps:	13/450 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 AAP----GNPNPADGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWL 81
            |:|    ||...:..:|.:.||::::|:|||.:|||.:||||||::|.||.:|:.|.|.||::|.
Zfish    12 ASPEVSNGNLKASSSQESMKLKKEISLLNGVCLIVGNMIGSGIFVSPKGVLMYSGSYGLSLVVWT 76

  Fly    82 TCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHY 146
            ..||.|..||||||||||.||:||..|||:|.:||..:.|:|||.:||||.||:|.::|::|::|
Zfish    77 IGGIFSVFGALCYAELGTTITKSGASYAYILEAFGGFLAFIRLWTSLLIIEPTSQAVIAITFSNY 141

  Fly   147 AVKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMA 211
            .|:|.||.|..|..|.:||||.|:.|||.:||..||...:|||.||..|::|||.:|::||..:.
Zfish   142 MVQPIFPTCIAPYVANRLLAAACICLLTFVNCAYVKYGTRVQDFFTYVKVVALIAVIITGLVKIF 206

  Fly   212 TGELENFRNPWEGIYT-----ARNIGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMP 271
            .|..:||    ||:::     ..::..|.||.||::.||:.|||||||:::|.:|||.||.|:||
Zfish   207 QGYTQNF----EGLFSDSSHDPGDVALALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIAISMP 267

  Fly   272 LVTSIYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGPLAFMVPIFVALSTFGGVNGVLFTSAR 336
            :||.||:|.||||:.::..|.:|.|.||||||.::|||.|.:.:|:.||.|.|||:|..:..::|
Zfish   268 IVTVIYILTNLAYYTILPIPAILDSDAVAVTFADQVFGYLNWTIPVAVAFSCFGGLNASIVAASR 332

  Fly   337 LFATGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFSSVLWLSVVASIA 401
            ||..|::|||||.:..:.|:.:.||||:|:|...|:|:.|..::|::||||:|...|..|..||.
Zfish   333 LFFVGSREGHLPDYLCMIHITRFTPIPALLFNGAMALVYLCVEDVFKLINYYSFSYWFFVGLSIL 397

  Fly   402 GMLWLRHKRPDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQNLLIGIGITLAGIPFYY 461
            |.|:||.|:||.|||:|:.|..||.|.:..|.||::|...:..|.||||||.|.|:|.|:
Zfish   398 GQLYLRWKQPDRPRPLKLSLFFPIIFCLCTVFLVVVPLYSDTINSLIGIGIALPGVPVYF 457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	210/439 (48%)
slc7a7	NP_001032648.1	2A0308	2..492	CDD:273332	214/449 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.690