DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JhI-21 and slc7a6

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	XP_005166451.1	Gene:	slc7a6 / 57957	ZFINID:	ZDB-GENE-000607-21	Length:	494	Species:	Danio rerio

Alignment Length:	466	Identity:	222/466 - (47%)
Similarity:	324/466 - (69%)	Gaps:	11/466 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GNP-NPA---DGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWLTCG 84
            |.| :||   ...|.:.||::::|:|||::|||.:||||||::|.||.||:.|.|.||:||...|
Zfish    12 GQPESPAALSKPRESMQLKKEISLLNGVSLIVGNMIGSGIFVSPKGVLIYSASYGLSLVIWAIGG 76

  Fly    85 ILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHYAVK 149
            |.|.:||||||||||.||:||..|||:|.|||..:.|:|||.:||||.||:|.::|::||:|.|:
Zfish    77 IFSVVGALCYAELGTTITKSGASYAYILESFGGFIAFIRLWTSLLIIEPTSQAVIAITFANYLVQ 141

  Fly   150 PFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMATGE 214
            |.||.|:||.:|.:|:||.|:.|||.||...||...:||||||..|:||||:||::|:..:..|.
Zfish   142 PLFPTCEPPYSASRLIAAACICLLTFINSAYVKWGTRVQDVFTYAKVLALIVIIITGIVKLCQGF 206

  Fly   215 LENFRNPWEGIYTARN---IGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTSI 276
            ..||.:.::|  ::|:   |..|.||.||::.||:.|||||||:::|.:|||.:|.|:||:||.|
Zfish   207 TINFEDSFQG--SSRDPGGIALALYSALFSYSGWDTLNFVTEEIKNPERNLPLSIAISMPIVTII 269

  Fly   277 YVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGPLAFMVPIFVALSTFGGVNGVLFTSARLFATG 341
            |:|.|:||:||::...:|:|.||||||.:...|.:::.:||.||||.:||:|..:..::|||..|
Zfish   270 YILTNVAYYAVLDMSAILASDAVAVTFADHTLGVMSWTIPIAVALSCYGGLNSSIIAASRLFFVG 334

  Fly   342 AQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFSSVLWLSVVASIAGMLWL 406
            |:|||||....:.|:::.||:|:|:|.|.|:|:.|..::|:|||||:|...|..|..||||.::|
Zfish   335 AREGHLPDALSMIHIERFTPVPALLFNCAMALIYLTVEDVFQLINYYSFSYWFFVGLSIAGQIYL 399

  Fly   407 RHKRPDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQNLLIGIGITLAGIPFYY--AFIARKKK 469
            |.|.||.|||:|:.|..||.|.:..|.||.:|...:..|.||||.|.|:|:|.|:  ..:...|:
Zfish   400 RWKEPDRPRPLKLSLVYPIIFCLCVVFLVAVPLYSDTLNSLIGIAIALSGVPVYFLGIHLPESKR 464

  Fly   470 PKCYGRLSNSV 480
            |....:|.:::
Zfish   465 PPIITKLLSAI 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	220/462 (48%)
slc7a6	XP_005166451.1	2A0308	2..489	CDD:273332	222/466 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.720