DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment JhI-21 and si:ch73-352p4.8

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	XP_697137.2	Gene:	si:ch73-352p4.8 / 568699	ZFINID:	ZDB-GENE-140106-36	Length:	492	Species:	Danio rerio

Alignment Length:	467	Identity:	191/467 - (40%)
Similarity:	292/467 - (62%)	Gaps:	1/467 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 TNGCAAPGNPNPADGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWL 81
            |:.....|....|..::.:.|:|::.|:..::.|:||::||||||||.||.:.:.|||.|||:|.
Zfish    10 TDKVCTDGGSEKAVKDDAVHLRRRIGLLPAISFIIGTVVGSGIFIAPKGVLMNSGSVGLSLLVWA 74

  Fly    82 TCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHY 146
            .||:|||.||||||||||..|:|||.|.|||.:.|||..|||||...:.|||...:.|:|:|..|
Zfish    75 LCGVLSTCGALCYAELGTSFTKSGGHYTYLLETLGPLPAFLRLWTEYIFIRPAVASYVSLAFGRY 139

  Fly   147 AVKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMA 211
            .|:|||..|..|...||:::.:.:|.:..:||.||.::.:.|...|..|:.||::||:.|:..:|
Zfish   140 VVEPFFMPCVAPTVLVKMVSMLGVTFVVAVNCWSVSLAARTQVSLTFIKMFALVLIIIPGIMALA 204

  Fly   212 TGELENFRNPWEG-IYTARNIGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAMPLVTS 275
            .|..:||:|.:|. ..:...:..||||||:|:|||.||||:|||:.:|.:.:|.||..:|..||.
Zfish   205 NGNTKNFQNAFESDSVSLTKLPLAFYSGLYAYGGWFYLNFITEEVINPNRTVPLAIIFSMVTVTV 269

  Fly   276 IYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGPLAFMVPIFVALSTFGGVNGVLFTSARLFAT 340
            .|||||:||:.::...|:|.|.||||||.||....:|..:|:.||||..|.:||..|.|.|:...
Zfish   270 FYVLVNVAYYTMMTANELLVSDAVAVTFANRALQGVAPAIPVLVALSCLGALNGGFFGSPRMLFV 334

  Fly   341 GAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFSSVLWLSVVASIAGMLW 405
            ||:|||||..|.:.|:::|||:|:::|...:.::|:....::||||:.|...||.:..:..|::.
Zfish   335 GAREGHLPAIFSMIHIRRQTPLPAVLFLYPLVIVMMARGEIFQLINFASFSRWLFIALATLGLII 399

  Fly   406 LRHKRPDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQNLLIGIGITLAGIPFYYAFIARKKKP 470
            .|::.|:.|||.||.:|:.:.|.:.|..:|.|....:|.|......:|::|:|.||..:.:...|
Zfish   400 HRYRFPEHPRPFKVPIAVAVVFTIVCFFIVGLSLYSDPWNTGGSCALTISGVPVYYLTVKKSCIP 464

  Fly   471 KCYGRLSNSVVE 482
            :.:.:..|.|.|
Zfish   465 ERWKKAFNYVSE 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	189/457 (41%)
si:ch73-352p4.8	XP_697137.2	2A0308	27..488	CDD:273332	188/450 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11785
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.930