Protein Alignment JhI-21 and SLC7A10

DIOPT Version :10

• Sequence 1: NP_609542.1
• Gene: JhI-21 / 34624
• FlyBaseID: FBgn0028425
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: XP_011525421.1
• Gene: SLC7A10 / 56301
• HGNCID: 11058
• Length: 660
• Species: Homo sapiens
• Alignment Length: 632
• Identity: 208/632 - (32%)
• Similarity: 311/632 - (49%)
• Gaps: 160/632 - (25%)

  Fly    24 GNPNPA-----------DGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSL 77
            |||.||           ...|::.||:::.|::...||:|.||||||||:|.||..::.|||.:|
Human    12 GNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLAL 76

  Fly    78 LIWLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALS 142
            .:|:..|.::.:|:|||||||..|.:|||||||:...||.|.|||.||.|:||:.||:..:::::
Human    77 FVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMT 141

  Fly   143 FAHYAVKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGL 207
            |::|.::|.||.|.||..|.::|:..||.|||.:|..||:.:.::||:||.||||||.:||..||
Human   142 FSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGL 206

  Fly   208 YYMATGELENFR--NPWEGIYTARNIGY---AFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIW 267
            ..:..|..|..|  |.: ..:...::|:   ||..|.|||.|||:||:||||:.|..|||||||:
Human   207 LQIFQGHFEELRPSNAF-AFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIF 270

  Fly   268 IAMPLVTSIYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGP---------------------- 310
            |::||||.:|...|:|||..::..|:|||.||||..| .:.||
Human   271 ISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVVSG-PLLGPWLLPRPLPRPYTWPLYCAHPDL 334

  Fly   311 ------LAFM----------------VPIFV---------------------------------- 319
                  |.|:                :|:.:
Human   335 RGEAAGLLFLGHACLRGSVNLRRDQWLPVHLLQVTALGRRGHGEGRLGCRCAPVMPWARGRDTCR 399

  Fly   320 ----------------ALSTFG---------------------------------GVNG------ 329
                            .|.|.|                                 |.:|
Human   400 GRGLPEAGMMIPHGNKCLITTGRQRKQEAGRLDEGENCPVGLLGPEQEVRGDSLRGTSGPKLRPR 464

  Fly   330 -----VLFTSARLFATGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFS 389
                 :...:|||..:||:|||||....:.||:..||||:|:..|..:.:::|..:.|.||||.|
Human   465 MWPVPISVPNARLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVS 529

  Fly   390 SVLWLSVVASIAGMLWLRHKRPDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQNLLIGIGITL 454
            .:.:|....:|.|:|.||.:||.|.|||||:|.:|:.::|....|::...:.||....:|:.|.|
Human   530 FINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIIL 594

  Fly   455 AGIPFYYAFIARKKKPKCYGRLSNSVV----EICRAIFNTTIIESNE 497
            .|:|.::..:..:.||||..||:.|:.    |:|..::.....|..|
Human   595 TGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPEEEE 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_609542.1	2A0308	27..494	CDD:273332	203/624 (33%)
SLC7A10	XP_011525421.1	2A0308	15..635	CDD:273332	203/621 (33%)