DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JhI-21 and Slc7a6

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	XP_006531198.1	Gene:	Slc7a6 / 330836	MGIID:	2142598	Length:	532	Species:	Mus musculus

Alignment Length:	462	Identity:	221/462 - (47%)
Similarity:	320/462 - (69%)	Gaps:	13/462 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 VEPTNGCAAPGNPNPADGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLL 78
            |:...|..:.|:|      |.:.||::::|:|||:::||.:||||||::|.||..||.|.|.||:
Mouse    41 VKEDAGSPSQGSP------ETMQLKKEISLLNGVSLVVGNMIGSGIFVSPKGVLKYTASYGLSLI 99

  Fly    79 IWLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSF 143
            :|...|:.|.:||||||||||.||:||..|||:|.:||..:.|:|||::|||:.||:|.|:|::|
Mouse   100 VWAIGGLFSVVGALCYAELGTTITKSGASYAYILEAFGGFIAFIRLWVSLLIVEPTSQAIIAITF 164

  Fly   144 AHYAVKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLY 208
            |:|.:||.||.||||..|.:||||.|:.|||.:||..||...:|||.||..|:||||.||:.||.
Mouse   165 ANYIIKPSFPTCDPPYVACRLLAAACVCLLTFVNCAYVKWGTRVQDTFTYAKVLALIAIIIMGLV 229

  Fly   209 YMATGELENFRNPWEGIYTARNIG---YAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIWIAM 270
            .:..|..|:|::.::|  ::.|:|   .|.||.||::.||:.|||||||:::|.:|||.||.|:|
Mouse   230 KLCQGHTEHFQDAFKG--SSWNVGDLSLALYSALFSYSGWDTLNFVTEEIKNPERNLPLAIGISM 292

  Fly   271 PLVTSIYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGPLAFMVPIFVALSTFGGVNGVLFTSA 335
            |:||.||:|.|:||:.|:|..::..|.||||||.::.||..::.:||.||||.|||:|..:|.|:
Mouse   293 PIVTLIYILTNVAYYTVLNIQDVHKSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASS 357

  Fly   336 RLFATGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFSSVLWLSVVASI 400
            |||..|::|||||....:.|:::.||:|:|:|.|.|:|:.|:..:|:.||||||...|..|..|:
Mouse   358 RLFFVGSREGHLPNLLSMIHIERFTPVPALLFNCTMTLIYLVVKDVFLLINYFSFSYWFFVGLSV 422

  Fly   401 AGMLWLRHKRPDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQNLLIGIGITLAGIPFYY--AF 463
            .|.|:||.|.||.|||:|:.|..||.|.|..:.||.:|...:..|.||||||.|:|:|.|:  .:
Mouse   423 VGQLYLRWKEPDWPRPLKLSLFFPIVFCVCSLFLVAVPLFSDTINSLIGIGIALSGVPVYFLGVY 487

  Fly   464 IARKKKP 470
            :...::|
Mouse   488 LPESRRP 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	217/449 (48%)
Slc7a6	XP_006531198.1	2A0308	34..518	CDD:273332	221/462 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.720