DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JhI-21 and Slc7a4

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001100548.1	Gene:	Slc7a4 / 303787	RGDID:	1305905	Length:	635	Species:	Rattus norvegicus

Alignment Length:	427	Identity:	112/427 - (26%)
Similarity:	186/427 - (43%)	Gaps:	81/427 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWLTCGILSTIGALCYAELGTCI 101
            |:|.|:.::...:.||.::|||:::. ||......:..:.||.:|...:.|.:.||||||.|..:
  Rat    33 LRRCLSTLDLTLLGVGGMVGSGLYVL-TGTVAKDMAGPAVLLSFLVAAVASLLAALCYAEFGARV 96

  Fly   102 TRSGGDYAYLLVSFGPLVGFLRLWIALL-----------------------IIRPTTQTIVAL-- 141
            .|:|..|.:..||.|.:..||..|..||                       .||..|::.:.:
  Rat    97 PRTGSAYLFTYVSMGEIWAFLIGWNVLLEYLIGGAAVARAWSGYLDAIFNHSIRNFTESHMGVWQ 161

  Fly   142 --SFAHYAVKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIIL 204
              ..|||   |.|           |.|.|.|.....::| ..:||..:...|:...|:.::.||:
  Rat   162 MPFLAHY---PDF-----------LAAGILLVASAFVSC-GARVSSWLNHTFSAISLIVILFIIV 211

  Fly   205 SGLYYMATGELENFRNPWEGIYTARNIGYA--FYSGL--------FAFGGWNYLNFVTEELQDPY 259
            .|..      |....|     ::|...|:|  .:||:        :||.|::.:...:||.::|.
  Rat   212 LGFI------LARPHN-----WSAEEGGFAPFGFSGILAGTATCFYAFVGFDVIAASSEEAKNPR 265

  Fly   260 KNLPRAIWIAMPLVTSIYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGPLAFMVPIFVALSTF 324
            ..:|.||.|::.|....|:||:.....:|....:....|:|..|..|.:|...|:    ||:.:.
  Rat   266 WAVPMAIAISLGLAAGAYILVSTVLTLMVPWHSLDPDSALADAFYRRGYGWAGFI----VAVGSI 326

  Fly   325 GGVNGV----LFTSARLFATGAQEGHLPKFFQLF---HVKQQTPIPS-LIFTCLMSLLMLLTD-- 379
            ..:|.|    ||:..|:....|.:|   .|||:|   |.:.|.|:.. |:|..||:||.||.|
  Rat   327 CAMNTVLLSNLFSLPRIVYAMAADG---LFFQVFARVHPRTQVPVVGILVFGVLMALLALLMDLE 388

  Fly   380 NVYQLINYFSSVLWLSVVASIAGMLWLRHKRPDLPRP 416
            .:.|.::..:.:.:..|..||..:.:.:...|..|.|
  Rat   389 ALVQFLSIGTLLAYTFVATSIIVLRFQKASPPSSPCP 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	112/427 (26%)
Slc7a4	NP_001100548.1	2A0303	14..592	CDD:273330	112/427 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920