DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment JhI-21 and Slc7a15

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001100184.1	Gene:	Slc7a15 / 298873	RGDID:	1560726	Length:	488	Species:	Rattus norvegicus

Alignment Length:	466	Identity:	189/466 - (40%)
Similarity:	290/466 - (62%)	Gaps:	11/466 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 EPTNGCAAPGNPNPADGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLI 79
            |..:|...|.......|...:.:||::.|.:.|::..|.:||||||::|.||.:|..|.|:||:|
  Rat     5 EEKDGSDKPEGQEQGSGAAGLTMKREIGLWSAVSMTAGCMIGSGIFMSPQGVLVYIGSPGASLII 69

  Fly    80 WLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIALLIIRPTTQTIVALSFA 144
            |.|||:|:.:|||||||||:.:..|||:|||:|.:||.|..||.::|.:|:.||...|.|:||||
  Rat    70 WATCGLLALLGALCYAELGSLVPESGGEYAYILRAFGSLPAFLVIYIIVLVGRPAAITAVSLSFA 134

  Fly   145 HYAVKPFFPECDP-PQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLY 208
            .||:.||:|.|.. ||..||::|..|:.:|..||..|.::|..:.:|.|..||.:|::|::.|..
  Rat   135 EYALAPFYPGCSSVPQVIVKIVACSCILVLLLINFWSSRMSTVLMNVCTAAKLFSLLVIVVGGAV 199

  Fly   209 YMATGELEN------FRNPWEGIYTARNIGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAIW 267
            .:|.|.:..      |.|..:   .|..||.|||.||::|.||:.:|.|.||:::|.:||..|:.
  Rat   200 GLAQGRIPTESLLFAFHNTTQ---QAGRIGMAFYQGLWSFDGWSNINTVIEEIKNPKQNLVWAVV 261

  Fly   268 IAMPLVTSIYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGPLAFMVPIFVALSTFGGVNGVLF 332
            ||:||||.:|||||::|..|::..|:|:|.|:|||:||:|.|..|::||:.|||||||.|||..|
  Rat   262 IAIPLVTILYVLVNISYLLVMSPSEILTSDAIAVTWGNQVLGSWAWLVPLAVALSTFGAVNGGFF 326

  Fly   333 TSARLFATGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFSSVLWLSVV 397
            :.:|:....|:|||:|:...:.||.:.||.|:||||..::||:::..|....:|..|.:.||:..
  Rat   327 SGSRVCYAAAREGHMPQLMSMIHVHRLTPAPALIFTTAVALLLVIPGNFSTFVNLLSFLSWLTYG 391

  Fly   398 ASIAGMLWLRHKRPDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQNLLIGIGI-TLAGIPFYY 461
            .:.|.:|:||.|..:|....||...:|:..::..:.|||.|.::.||...:.|.: .|.|.|.|:
  Rat   392 TTFACLLYLRIKTRNLHHTYKVPTFIPVIMLLVSLYLVLAPIIDHPQMEFLYIFLFVLTGFPVYF 456

  Fly   462 AFIARKKKPKC 472
            .....:.:.||
  Rat   457 LLFHFQCQSKC 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	186/454 (41%)
Slc7a15	NP_001100184.1	2A0308	4..481	CDD:273332	189/466 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D621852at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.830