DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment JhI-21 and meu22

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_596348.1	Gene:	meu22 / 2540779	PomBaseID:	SPBC19F8.06c	Length:	574	Species:	Schizosaccharomyces pombe

Alignment Length:	498	Identity:	103/498 - (20%)
Similarity:	183/498 - (36%)	Gaps:	108/498 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 PADGEEKIVLKRKLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWLTCG--ILSTIG 90
            |...|:...|:|||...:...|.:|..:|:|:|:. :|..:......|.|:.:...|  :|.|..
pombe    49 PLQPEDTQDLQRKLKPRHMQMIAIGGCVGTGLFVG-SGNALADGGPASILIAFAVIGTYVLFTTS 112

  Fly    91 ALCYAELGTCITRSGGDYAYLLVSFGPLVGF---LRLWIALLIIRPTTQTIVALSFAHYAVKPFF 152
            ||  |||......||..|.|......|..||   ::.|::..:..|...|:..|      :..|:
pombe   113 AL--AELSAIYPVSGSFYTYFSKFIDPAWGFAVGIQYWLSFAVTVPLELTVAPL------IINFW 169

  Fly   153 PECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTVGKLLALIMIILSGLYYMATGELEN 217
            ....|    |.:..::...::..||....:...:|:...::.|::::|..::..:...|.|...:
pombe   170 NASGP----VSIWISVFYVIIIAINIWGTEGYGEVEFFLSIMKVISVIGFVILSIIIAAGGVPTD 230

  Fly   218 ---------------FRNPWEGIYTARNIGYAFYSGLFAFGGWNYLNFVTEELQDPYKNLPRAI- 266
                           |.|.::|:.....|      .:|:..|...:.....|.::|.|.:|.|:
pombe   231 DRGVIGVSYWKQPLVFNNGFKGLCAVSVI------AIFSLSGTELVGLAASEAKNPQKTVPAAVK 289

  Fly   267 ---WIAMPLVTSIYVLVNLAYFAVV--------------NKPEMLSSLAVAVTFGNRVFGPLAFM 314
               |       .|::...:|.|.:.              |...::|...:|:...|  ...|..:
pombe   290 QIFW-------RIFLFYIVALFMLTLVVPSDLPGLRTSDNSNVLISPFVIAIQLAN--IRALPSI 345

  Fly   315 VPIFVALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTD 379
            :.:.:.|||....|...:.::|.....|:.|:.||.|...: |:..||.::..|.|...:...|:
pombe   346 MNVVILLSTLSVGNSASYAASRALFALAKNGYAPKIFNKTN-KRGHPIYAIAVTLLFGSIAYFTE 409

  Fly   380 NVY--QLINYFSSVLWLSVVASIAGMLWLRH------------KRPDLP-RPIKVHLALPITFMV 429
            ...  .|..:..|:..|| ...|.|.:.|.|            |..||| |.|         |.|
pombe   410 AGVGGALFGWLLSICGLS-TTFIWGSICLAHIQFRRAWKIQNRKLEDLPYRSI---------FGV 464

  Fly   430 SCVTLVLLPNLEEPQNLLIGIGITLAGI--PFYYAFIARKKKP 470
                          ...:.|:.:|:..:  .||.|.....|||
pombe   465 --------------YGSIYGVAMTILALIAQFYVAVFPIGKKP 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	103/498 (21%)
meu22	NP_596348.1	LysP	17..544	CDD:223903	103/498 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2200
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.040