Protein Alignment JhI-21 and SLC7A11

DIOPT Version :10

• Sequence 1: NP_609542.1
• Gene: JhI-21 / 34624
• FlyBaseID: FBgn0028425
• Length: 500
• Species: Drosophila melanogaster
• Sequence 2: XP_011530104.1
• Gene: SLC7A11 / 23657
• HGNCID: 11059
• Length: 506
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 46/252 - (18%)
• Similarity: 96/252 - (38%)
• Gaps: 62/252 - (24%)

  Fly   242 DSSSCNQVVDLLKQLAKQGRTIICTIHQ--PSAKLFQEFDQVYVLSNGECMYQGCTNSLVPFLQS 304
            |.....:|.|:...|.:...||:..:..  |..:          |:|.|..::      |.::.|
Human    26 DGEKATKVQDIKNNLKEAIETIVAAMSNLVPPVE----------LANPENQFR------VDYILS 74

  Fly   305 VDMPCPVYHNPADYVIELACGEYGEERIQRMVMEMGNG----ECTEWFTDKRKLLKPEQLRQKYP 365
            | |..|.:..|.:: .|.|...:.:|.: |...|..|.    :|.::|.||..::|...
Human    75 V-MNVPDFDFPPEF-YEHAKALWEDEGV-RACYERSNEYQLIDCAQYFLDKIDVIKQAD------ 130

  Fly   366 LKKIIEQNEDL----TATSQVHQLQVLI----------------KRGIIKAKRDATLTHLRIGVN 410
               .:..::||    ..||.:.:.:..:                :|..|:...|.|      .:.
Human   131 ---YVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVT------AII 186

  Fly   411 IIIAAMLGFLFIDAGNEGSRVLDNYNLLFSILMHHMMATMMLTVLTFPTEMGVILKE 467
            .::|:....:.|...|:.:|:.:..||..||..:..:.|  ::|:.|..:..::.::
Human   187 FVVASSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRT--ISVILFLNKQDLLAEK 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_609542.1	2A0308	27..494	CDD:273332	46/252 (18%)
SLC7A11	XP_011530104.1	2A0308	1..483	CDD:273332	46/252 (18%)