DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment JhI-21 and aat-8

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_500425.2	Gene:	aat-8 / 185079	WormBaseID:	WBGene00000009	Length:	483	Species:	Caenorhabditis elegans

Alignment Length:	475	Identity:	155/475 - (32%)
Similarity:	247/475 - (52%)	Gaps:	26/475 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 KLTLINGVAIIVGTIIGSGIFIAPTGVFIYTESVGSSLLIWLTCGILSTIGALCYAELGTCITRS 104
            |:.||...:.|||:||||||||||.|:..:..|||.||:||:.|.:|:.|.|:.|.||||.|..|
Worm     8 KIGLIGATSYIVGSIIGSGIFIAPKGIVEHAGSVGLSLIIWVFCALLNMITAINYIELGTSIPES 72

  Fly   105 GGDYAYL-LVSFGPLVGFLRLWIALLIIRPTTQTIVALSFAHYAVKPFFP----ECDPPQNAVKL 164
            |.|.||: .:.:.| :.|..||::|||...::..::.|:|..|.|:...|    ......|..||
Worm    73 GADLAYIDYMGWTP-IAFSLLWLSLLIQSSSSAAVLYLTFGKYLVQALEPIVCFTSSGADNCAKL 136

  Fly   165 LAAICLTLLTTINCLSV-KVSMKVQDVFTVGKLLALIMIILSGLYYMA-TGELENFR-------N 220
            .....|..||..|..|: |.:.:||.:....|:.|.::||..|.:::. .|...::|       :
Worm   137 FGFGLLLFLTLTNMFSLNKFAARVQIISMCSKIFATLIIIGIGFFFIIFRGATSHYRSSEIMKGS 201

  Fly   221 PWEGIYTARNIGYAFYSGLFAFGGWNYLNFVTEELQ--DPYKNLPRAIWIAMPLVTSIYVLVNLA 283
            .|    .|..|..|.|.|.:||||:..||:.|||:|  :..|.||||....:.:...||||||::
Worm   202 DW----NAGAIALAIYQGNWAFGGFTTLNYGTEEIQIENFRKTLPRACLGGLLISAVIYVLVNVS 262

  Fly   284 YFAVVNKPEMLSSLAVAVTFGNRVF--GPLAFMVPIFVALSTFGGVNGVLFTSARLFATGAQEGH 346
            |||::...|::.|.|||.||..|..  || ||.||..|.....|.:||.:|..:|....|::...
Worm   263 YFAILTPQEIIDSSAVATTFIQRTVGNGP-AFAVPAVVGFLLVGTLNGDVFGWSRYMVAGSRRKM 326

  Fly   347 LPKFFQLFHVKQQTPIPSLIFTCLMSLLMLLTDNVYQLINYFSSVLWLSVVASIAGMLWLRHKR- 410
            :|..|.|.||...:|..|:.|..|.|::.....:..||::|.:....|:.:.::..::.::.|:
Worm   327 MPTCFSLIHVDNDSPRVSVFFHTLTSIIFAFMGDTDQLVDYLTVTGMLTTIFALLVLVIIKWKKM 391

  Fly   411 PDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQNLLIGIGITLAGIPFYYAFIARKKKPKCYGR 475
            |....|:|..:..||..:|..:.|:::|..::|.:.:||..:.|.|:..|:.........:..|.
Worm   392 PIASDPVKYSIFWPILNLVIMIALLVIPIQQDPLSSIIGFSMFLGGVVVYFIIKFVVSHTEFLGV 456

  Fly   476 LSNSVVEICRAIFNTTIIES 495
            :...:..:|: |...||::|
Worm   457 IDEKLTHLCQ-ILTWTIVDS 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	154/472 (33%)
aat-8	NP_500425.2	AA_permease_2	9..438	CDD:290254	146/434 (34%)
aat-8	NP_500425.2	PT_UbiA	<241..>324	CDD:294241	34/83 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D621852at2759
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.830