DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment JhI-21 and aat-3

DIOPT Version :9

Sequence 1:	NP_001245996.1	Gene:	JhI-21 / 34624	FlyBaseID:	FBgn0028425	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001300351.1	Gene:	aat-3 / 180557	WormBaseID:	WBGene00000004	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	505	Identity:	238/505 - (47%)
Similarity:	338/505 - (66%)	Gaps:	19/505 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NGVTTSLVEPTNG---CAAPGNPNPAD--GEEKI---VLKRKLTLINGVAIIVGTIIGSGIFIAP 63
            :|.||  :.|..|   .:.|.|..|::  .:|::   .|::.:||.|||:||||.||||||||:|
Worm    28 DGHTT--IRPKMGKQEQSEPLNQEPSNEHHDEEVGDKGLEKTMTLFNGVSIIVGCIIGSGIFISP 90

  Fly    64 TGVFIYTESVGSSLLIWLTCGILSTIGALCYAELGTCITRSGGDYAYLLVSFGPLVGFLRLWIAL 128
            ||:.....|||.||::|:..|:.:.|||.|||||||.|.:|||||||::.:|||.:.||||||..
Worm    91 TGIQAQAGSVGLSLIVWVLSGLFAGIGAFCYAELGTLIRKSGGDYAYIMEAFGPFLAFLRLWIES 155

  Fly   129 LIIRPTTQTIVALSFAHYAVKPFFPECDPPQNAVKLLAAICLTLLTTINCLSVKVSMKVQDVFTV 193
            :::||.|.|||||:||.|.:|||:|:||.|..:.:|:||:.|.|||.:||:|||.:.||||.|.|
Worm   156 IVVRPCTATIVALTFAIYMLKPFYPDCDSPPLSTELIAALLLVLLTAVNCISVKWASKVQDFFFV 220

  Fly   194 GKLLALIMIILSGLYYMATGELENFRNPWEGIY--TARNI---GYAFYSGLFAFGGWNYLNFVTE 253
            .|..||::||.:||:.|.:|:.|.| :.:|.|:  ||:::   ..||||||||:.|||||||:.|
Worm   221 TKTAALVLIIFTGLWNMVSGKPEAF-DSFENIFENTAKDLETASLAFYSGLFAYQGWNYLNFIVE 284

  Fly   254 ELQDPYKNLPRAIWIAMPLVTSIYVLVNLAYFAVVNKPEMLSSLAVAVTFGNRVFGPLAFMVPIF 318
            |||:|.:|||.:|.|:..|.|.||.|.|:|.:..:...|||:|.||||.|..:.:|..||.:|||
Worm   285 ELQNPKRNLPLSIAISCSLCTIIYTLTNVALYTSITPDEMLASPAVAVLFAEKNYGWFAFCMPIF 349

  Fly   319 VALSTFGGVNGVLFTSARLFATGAQEGHLPKFFQLFHVKQQTPIPSLIFTCLMSLL-MLLTDNVY 382
            ||.||.|..|||:.||:|||..||:||.:|....:.:...:||||::|.|.|:||| :||::|:|
Worm   350 VACSTIGSANGVILTSSRLFYCGAREGQMPNVLTMVNKTTKTPIPAVILTGLLSLLYLLLSNNIY 414

  Fly   383 QLINYFSSVLWLSVVASIAGMLWLRHKRPDLPRPIKVHLALPITFMVSCVTLVLLPNLEEPQNLL 447
            .||||.....|:::..:|..:.:.|...||.||.:|..:..||.|.:.||.|||:|.|..|::..
Worm   415 SLINYIQVSYWIAIGGAILALFYFRKTMPDAPRAVKAPIVFPIIFFIGCVLLVLVPVLGNPKDTA 479

  Fly   448 IGIGITLAGIPFYYAFIARKKKPKCYGRLSNSVVEICRAIFNTTIIESNE 497
            |||.|.|:|:|.|..|||.|.||||...|::||....:.:|  .::::|:
Worm   480 IGILIMLSGVPVYLIFIAWKGKPKCIDSLTDSVTIFTQKLF--MVVDANK 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
JhI-21	NP_001245996.1	AA_permease_2	27..494	CDD:330980	230/477 (48%)
aat-3	NP_001300351.1	2A0308	40..527	CDD:273332	232/489 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53617
OrthoDB	1	1.010	-	-		D339093at33208
OrthoFinder	1	1.000	-	-		FOG0000064
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100314
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X75
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730